A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining
Uterine metastases from extragenital sites are rare. We present a case of a woman who had undergone surgery for small intestinal cancer and subsequently developed metastases in her left ovary and uterus. A nulliparous woman in her 50s underwent laparoscopic partial small bowel resection with lymph n...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2024/8551816 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841564784058695680 |
|---|---|
| author | Sachiko Nagao Motoki Matsuura Shoko Kurokawa Masato Tamate Taishi Akimoto Tsuyoshi Saito |
| author_facet | Sachiko Nagao Motoki Matsuura Shoko Kurokawa Masato Tamate Taishi Akimoto Tsuyoshi Saito |
| author_sort | Sachiko Nagao |
| collection | DOAJ |
| description | Uterine metastases from extragenital sites are rare. We present a case of a woman who had undergone surgery for small intestinal cancer and subsequently developed metastases in her left ovary and uterus. A nulliparous woman in her 50s underwent laparoscopic partial small bowel resection with lymph node dissection for small intestinal cancer. Five months later, computed tomography (CT) revealed a left ovarian tumor and ascites. She underwent bilateral adnexectomy and adjuvant chemotherapy, and the ovarian tumor was diagnosed as a small intestinal cancer metastasis. Two years after the small intestinal cancer surgery, a positron emission tomography (PET)-CT scan revealed a uterine accumulation. Cervical cytology was negative for intraepithelial lesion or malignancy. Endometrial histology showed an adenocarcinoma of the uterus. The patient underwent total abdominal hysterectomy followed by adjuvant chemotherapy. Histopathology and immunohistochemistry of the uterine tumor revealed that it was a metastasis of small intestinal cancer (Cytokeratin 7 [CK7] [−], Cytokeratin 20 [CK20] [+], Special AT-Rich Sequence-Binding Protein 2 [SATB2] [+], Paired Box Gene 2 [PAX2] [−], and estrogen receptor [ER] [−]). In patients with cancer, histopathology and immunohistochemistry are important for distinguishing between primary and metastatic tumors and for guiding the choice of treatment. |
| format | Article |
| id | doaj-art-5fc937d6904e43c9a703540ef2271709 |
| institution | Kabale University |
| issn | 2090-6714 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-5fc937d6904e43c9a703540ef22717092025-01-02T22:33:56ZengWileyCase Reports in Oncological Medicine2090-67142024-01-01202410.1155/2024/8551816A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using ImmunostainingSachiko Nagao0Motoki Matsuura1Shoko Kurokawa2Masato Tamate3Taishi Akimoto4Tsuyoshi Saito5Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyUterine metastases from extragenital sites are rare. We present a case of a woman who had undergone surgery for small intestinal cancer and subsequently developed metastases in her left ovary and uterus. A nulliparous woman in her 50s underwent laparoscopic partial small bowel resection with lymph node dissection for small intestinal cancer. Five months later, computed tomography (CT) revealed a left ovarian tumor and ascites. She underwent bilateral adnexectomy and adjuvant chemotherapy, and the ovarian tumor was diagnosed as a small intestinal cancer metastasis. Two years after the small intestinal cancer surgery, a positron emission tomography (PET)-CT scan revealed a uterine accumulation. Cervical cytology was negative for intraepithelial lesion or malignancy. Endometrial histology showed an adenocarcinoma of the uterus. The patient underwent total abdominal hysterectomy followed by adjuvant chemotherapy. Histopathology and immunohistochemistry of the uterine tumor revealed that it was a metastasis of small intestinal cancer (Cytokeratin 7 [CK7] [−], Cytokeratin 20 [CK20] [+], Special AT-Rich Sequence-Binding Protein 2 [SATB2] [+], Paired Box Gene 2 [PAX2] [−], and estrogen receptor [ER] [−]). In patients with cancer, histopathology and immunohistochemistry are important for distinguishing between primary and metastatic tumors and for guiding the choice of treatment.http://dx.doi.org/10.1155/2024/8551816 |
| spellingShingle | Sachiko Nagao Motoki Matsuura Shoko Kurokawa Masato Tamate Taishi Akimoto Tsuyoshi Saito A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining Case Reports in Oncological Medicine |
| title | A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining |
| title_full | A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining |
| title_fullStr | A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining |
| title_full_unstemmed | A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining |
| title_short | A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining |
| title_sort | rare case of small intestinal cancer with uterine metastasis after surgery for ovarian metastasis diagnosed using immunostaining |
| url | http://dx.doi.org/10.1155/2024/8551816 |
| work_keys_str_mv | AT sachikonagao ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT motokimatsuura ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT shokokurokawa ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT masatotamate ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT taishiakimoto ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT tsuyoshisaito ararecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT sachikonagao rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT motokimatsuura rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT shokokurokawa rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT masatotamate rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT taishiakimoto rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining AT tsuyoshisaito rarecaseofsmallintestinalcancerwithuterinemetastasisaftersurgeryforovarianmetastasisdiagnosedusingimmunostaining |