Investigating the shared genetic architecture between schizophrenia and sex hormone traits

Investigating the shared genetic architecture between schizophrenia and sex hormone traits

Abstract Sex hormones are involved in schizophrenia pathogenesis; however, their direction and genetic overlap remain unknown. By leveraging summary statistics from large-scale genome-wide association studies, we quantified the shared genetic architecture between schizophrenia and four sex hormone t...

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Main Authors: Xiaoyan He, Qingyan Ma, Jing Liu, Pu Lei, Huan Peng, Wen Lu, Yixin Liu, Xianyan Zhan, Bin Yan, Xiancang Ma, Jian Yang
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03305-7
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