Interleukin-27 Ameliorates Atherosclerosis in ApoE-/- Mice through Regulatory T Cell Augmentation and Dendritic Cell Tolerance

Atherosclerosis, which is characterized by chronic inflammation in the arterial wall, is driven by immune cells and cytokines. Recent evidence indicated that interleukin (IL)-27 showed pleiotropic properties in immune diseases. However, precise mechanisms of IL-27, especially in atherosclerosis rema...

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Bibliographic Details
Main Authors: Wenbin Xu, Ruirui Zhu, Zhengfeng Zhu, Kunwu Yu, Yue Wang, Yan Ding, Jian Yu, Hongxia Tang, Qiutang Zeng, Yucheng Zhong
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/2054879
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