Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India
Background: In the last few decades ischemic stroke in young adults (15-45 years) has been increasingly reported. This study was aimed to evaluate the epidemiological features, risk factors and mechanisms of ischemic stroke in young adults. Methods: From June 2018 to February 2020, patients diagn...
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KIMS Foundation and Research Center
2025-06-01
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| Series: | Journal of Medical and Scientific Research |
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| author | Konda M Varalakshmi EA Patil A Kaul S Yada PK Jayasree M Sitajayalakshmi S Surath M |
| author_facet | Konda M Varalakshmi EA Patil A Kaul S Yada PK Jayasree M Sitajayalakshmi S Surath M |
| author_sort | Konda M |
| collection | DOAJ |
| description | Background: In the last few decades ischemic stroke in young adults (15-45 years) has been increasingly reported. This study was aimed to evaluate the epidemiological features, risk factors and mechanisms of ischemic stroke in young adults.
Methods: From June 2018 to February 2020, patients diagnosed with ischemic stroke in the age group of 15-45 years from a tertiary care referral hospital in Hyderabad, India, were consecutively enrolled to study their risk factors, mechanisms and outcome.
Results: Out of 971 patients of ischemic strokes 164 (16.8%) were young adults, among whom 113 (69%) were in the age group 36-45 years. Males constituted 71.3% of cohort. Risk factors were alcohol abuse (39.63%), dyslipidemia (39.02%), hypertension (32.32%), smoking (27.44%), diabetes (25.61%), family history of stroke (23.78%) and past history of stroke (12.20%). As regards subtypes, large artery atherosclerosis constituted 26.22%, lacunar stroke 15.24%, cardio- embolic strokes 15.85%, stroke of other etiology 18.9% and stroke of unknown etiology 23.78%. At the time of discharge, death and dependency in younger adults was 8.53% and 45.12% respectively.
Conclusion: About 90% of young adults with ischemic stroke had at least 1 established modifiable vascular risk factor. Large artery atherosclerosis both intra and extra-cranial was the most frequent mechanism. Stroke due to other etiologies unique to young adults constituted about one fifth of all ischemic strokes.
Keywords: acute ischemic stroke; stroke in young; cerebrovascular accident; etiologies |
| format | Article |
| id | doaj-art-5fb4658eb4f64b59ae351f10f13c8785 |
| institution | Kabale University |
| issn | 2321-1326 2394-112X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | KIMS Foundation and Research Center |
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| series | Journal of Medical and Scientific Research |
| spelling | doaj-art-5fb4658eb4f64b59ae351f10f13c87852025-08-20T03:31:30ZengKIMS Foundation and Research CenterJournal of Medical and Scientific Research2321-13262394-112X2025-06-01132101106http://dx.doi.org/10.17727/JMSR.2024/13-18Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of IndiaKonda M0Varalakshmi EA1Patil A2Kaul S3Yada PK4Jayasree M5Sitajayalakshmi S6Surath M7Department of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaDepartment of Neurology, Krishna Institute of Medical Sciences, Minister Road, Secunderabad-500003, Telangana, IndiaBackground: In the last few decades ischemic stroke in young adults (15-45 years) has been increasingly reported. This study was aimed to evaluate the epidemiological features, risk factors and mechanisms of ischemic stroke in young adults. Methods: From June 2018 to February 2020, patients diagnosed with ischemic stroke in the age group of 15-45 years from a tertiary care referral hospital in Hyderabad, India, were consecutively enrolled to study their risk factors, mechanisms and outcome. Results: Out of 971 patients of ischemic strokes 164 (16.8%) were young adults, among whom 113 (69%) were in the age group 36-45 years. Males constituted 71.3% of cohort. Risk factors were alcohol abuse (39.63%), dyslipidemia (39.02%), hypertension (32.32%), smoking (27.44%), diabetes (25.61%), family history of stroke (23.78%) and past history of stroke (12.20%). As regards subtypes, large artery atherosclerosis constituted 26.22%, lacunar stroke 15.24%, cardio- embolic strokes 15.85%, stroke of other etiology 18.9% and stroke of unknown etiology 23.78%. At the time of discharge, death and dependency in younger adults was 8.53% and 45.12% respectively. Conclusion: About 90% of young adults with ischemic stroke had at least 1 established modifiable vascular risk factor. Large artery atherosclerosis both intra and extra-cranial was the most frequent mechanism. Stroke due to other etiologies unique to young adults constituted about one fifth of all ischemic strokes. Keywords: acute ischemic stroke; stroke in young; cerebrovascular accident; etiologieshttps://jmsronline.com/archive-article/Risk-factors-subtypes-ischemic-strokes-young-adults-Indiaacute ischemic strokestroke in youngcerebrovascular accidentetiologies |
| spellingShingle | Konda M Varalakshmi EA Patil A Kaul S Yada PK Jayasree M Sitajayalakshmi S Surath M Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India Journal of Medical and Scientific Research acute ischemic stroke stroke in young cerebrovascular accident etiologies |
| title | Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India |
| title_full | Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India |
| title_fullStr | Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India |
| title_full_unstemmed | Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India |
| title_short | Risk factors and subtypes of ischemic strokes in young adults: A tertiary care hospital study from southern part of India |
| title_sort | risk factors and subtypes of ischemic strokes in young adults a tertiary care hospital study from southern part of india |
| topic | acute ischemic stroke stroke in young cerebrovascular accident etiologies |
| url | https://jmsronline.com/archive-article/Risk-factors-subtypes-ischemic-strokes-young-adults-India |
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