Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson’s disease: Stage-specific patterns and dopaminergic correlates

Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson’s disease: Stage-specific patterns and dopaminergic correlates

Background: Previous research revealed differences in cerebellar white matter integrity by disease stages, indicating a compensatory role in Parkinson’s disease (PD). However, the temporal evolution of cerebellar white matter microstructure in patients with PD (PwPD) remains unclear. Objective: To u...

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Main Authors: Chentao He, Rui Yang, Siming Rong, Piao Zhang, Xi Chen, Qi Qi, Ziqi Gao, Yan Li, Hao Li, Frank-Erik de Leeuw, Anil M. Tuladhar, Marco Duering, Rick C. Helmich, Rick van der Vliet, Sirwan K.L. Darweesh, Zaiyi Liu, Lijuan Wang, Mengfei Cai, Yuhu Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
Parkinson’s disease
Cerebellar peduncles
Microstructural integrity
Compensation
Dopaminergic degeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158224001207
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