Function of non-coding RNA in radioresistance in non-small cell lung cancer
Lung cancer is not only one of the most common malignancies，but also has the highest mortality rate worldwide，among which non-small cell lung cancer（NSCLC）is the most common subtype. Radiation therapy is one of the main treatments for patients with advanced NSCLC，and the resistance generated during...
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| Main Author: | |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of New Medicine
2025-05-01
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| Series: | Xin yixue |
| Subjects: | |
| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1748392725663-948022661.pdf |
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| Summary: | Lung cancer is not only one of the most common malignancies，but also has the highest mortality rate worldwide，among which non-small cell lung cancer（NSCLC）is the most common subtype. Radiation therapy is one of the main treatments for patients with advanced NSCLC，and the resistance generated during long-term treatment is the key to radiation therapy failure and poor prognosis. With the widespread application of whole genome and RNA sequencing technology and the in-depth exploration of the biological functions of non-coding RNA（ncRNA），there is growing evidence that ncRNA are key regulators in tumorigenesis and development，and different ncRNAs play a role in promoting or inhibiting tumor radioresistance，which are expected to become a useful markers for tumor diagnosis and new targets for tumor treatment. In this article，recent research progress in ncRNA such as microRNA（miRNA），long non-coding RNA（lncRNA），and circular RNA（circRNA）in the radioresistance of NSCLC was reviewed. |
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| ISSN: | 0253-9802 |