Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants

Aim. Congenital corneal opacities (CCOs) are the major causes of early visual deprivation in infants. Balloon ultrasound biomicroscopy (UBM) examination is an effective method to diagnose CCO. However, whether it is suitable for children examination is still unknown. Methods. 26 Peters’ anomaly (PA)...

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Main Authors: Wen-Si Chen, Dao-Man Xiang, Lan-Xiang Hu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2020/8346981
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author Wen-Si Chen
Dao-Man Xiang
Lan-Xiang Hu
author_facet Wen-Si Chen
Dao-Man Xiang
Lan-Xiang Hu
author_sort Wen-Si Chen
collection DOAJ
description Aim. Congenital corneal opacities (CCOs) are the major causes of early visual deprivation in infants. Balloon ultrasound biomicroscopy (UBM) examination is an effective method to diagnose CCO. However, whether it is suitable for children examination is still unknown. Methods. 26 Peters’ anomaly (PA) or Rieger’s anomaly (RA) infants with congenital corneal opacities (CCO) (40 eyes) underwent UBM examinations to study their imaging features. Results. Based on the results, they were divided into UBM Dx-Type I: Descemet’s membrane (DM) and endothelium have heterogenous or discontinuous echo accompanied with corneal stroma echo-enhanced or shallow anterior chamber. Type II: Type I alteration plus abnormal strand of iris extended to the border of the posterior corneal defect or iridocorneal adhesion. Type III: Type I or II combined with the abnormal hyperechoic lens, lens luxation, or keratolenticular adhesion. Type IV: echoes of the DM and the endothelium are continuous, corneal stroma echo is enhanced, and an abnormal strand of peripheral iris extends to the prominent Schwalbe line, accompanied by iris stroma or pupil heteromorphism and a shallow or flat anterior chamber. Conclusion. UBM not only could accurately evaluate the anterior segment abnormalities in CCO infants but also would be a step forward for the management of PA- and RA-associated CCO.
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spelling doaj-art-5fa4da23abf048619a3ff0cce542fea92025-02-03T01:05:06ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/83469818346981Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in InfantsWen-Si Chen0Dao-Man Xiang1Lan-Xiang Hu2Department of Pediatric Ophthalmology, Guangzhou Children’s Hospital & Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Pediatric Ophthalmology, Guangzhou Children’s Hospital & Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Pediatric Ophthalmology, Guangzhou Children’s Hospital & Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, No. 9 Jinsui Road, Guangzhou 510623, ChinaAim. Congenital corneal opacities (CCOs) are the major causes of early visual deprivation in infants. Balloon ultrasound biomicroscopy (UBM) examination is an effective method to diagnose CCO. However, whether it is suitable for children examination is still unknown. Methods. 26 Peters’ anomaly (PA) or Rieger’s anomaly (RA) infants with congenital corneal opacities (CCO) (40 eyes) underwent UBM examinations to study their imaging features. Results. Based on the results, they were divided into UBM Dx-Type I: Descemet’s membrane (DM) and endothelium have heterogenous or discontinuous echo accompanied with corneal stroma echo-enhanced or shallow anterior chamber. Type II: Type I alteration plus abnormal strand of iris extended to the border of the posterior corneal defect or iridocorneal adhesion. Type III: Type I or II combined with the abnormal hyperechoic lens, lens luxation, or keratolenticular adhesion. Type IV: echoes of the DM and the endothelium are continuous, corneal stroma echo is enhanced, and an abnormal strand of peripheral iris extends to the prominent Schwalbe line, accompanied by iris stroma or pupil heteromorphism and a shallow or flat anterior chamber. Conclusion. UBM not only could accurately evaluate the anterior segment abnormalities in CCO infants but also would be a step forward for the management of PA- and RA-associated CCO.http://dx.doi.org/10.1155/2020/8346981
spellingShingle Wen-Si Chen
Dao-Man Xiang
Lan-Xiang Hu
Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
Journal of Ophthalmology
title Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
title_full Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
title_fullStr Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
title_full_unstemmed Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
title_short Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants
title_sort ultrasound biomicroscopy detects peters anomaly and rieger s anomaly in infants
url http://dx.doi.org/10.1155/2020/8346981
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AT daomanxiang ultrasoundbiomicroscopydetectspetersanomalyandriegersanomalyininfants
AT lanxianghu ultrasoundbiomicroscopydetectspetersanomalyandriegersanomalyininfants