Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea
Objective To analyze the microbiological and clinical characteristics of vulvovaginitis in girls, distinguishing between the premenarcheal and postmenarcheal groups in a tertiary center in South Korea. Methods This retrospective cohort study included 195 patients under 20 years of age diagnosed with...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Obstetrics and Gynecology
2025-03-01
|
| Series: | Obstetrics & Gynecology Science |
| Subjects: | |
| Online Access: | http://www.ogscience.org/upload/pdf/ogs-24215.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849309667642048512 |
|---|---|
| author | Soo Jin Park Ki Wook Yun Ji Yeon Han Sung Woo Kim Jae Hyeon Park Hoon Kim Eun Hwa Choi Seung-Yup Ku |
| author_facet | Soo Jin Park Ki Wook Yun Ji Yeon Han Sung Woo Kim Jae Hyeon Park Hoon Kim Eun Hwa Choi Seung-Yup Ku |
| author_sort | Soo Jin Park |
| collection | DOAJ |
| description | Objective To analyze the microbiological and clinical characteristics of vulvovaginitis in girls, distinguishing between the premenarcheal and postmenarcheal groups in a tertiary center in South Korea. Methods This retrospective cohort study included 195 patients under 20 years of age diagnosed with vulvovaginitis at a tertiary hospital between 2014 and 2023. The patients were categorized into premenarcheal (n=95) and postmenarcheal (n=100) groups. Data on initial symptoms, microbial cultures, and treatment methods were analyzed. Results The most common initial symptom was vaginal discharge, reported in 63.1% of cases. Culture results showed a 51.3% positivity rate for any microorganism, with a prevalence of gram-negative rods (32.8%) and gram-positive cocci (14.4%). The most frequently isolated microorganisms were Escherichia coli (17.9%), Candida albicans (7.7%), and Enterococcus faecalis (6.7%). Gram-negative rods were more common in the premenarcheal group (37.1% vs. 25.0%; P=0.01). No significant differences were observed in the prevalence of gram-positive cocci and Candida species between the two groups (16.8% vs. 12.0%, P=0.22; 6.3% vs. 13.0%, P=0.09; respectively). The susceptibilities of gram-positive microorganisms to penicillin, oxacillin, clindamycin, vancomycin, and tetracycline were 58.8%, 58.3%, 94.7%, 100.0%, and 73.7%, respectively. The susceptibilities of gram-negative microorganisms to amoxicillin/clavulanic acid, ciprofloxacin, ceftriaxone, and nitrofurantoin were 89.3%, 85.3%, 76.0%, and 100.0%, respectively. Conclusion This study identified differences in the microbial profiles associated with vulvovaginitis between premenarcheal and postmenarcheal girls. Age-specific and history-based clinical approaches tailored to menarcheal status are warranted to improve the management and outcomes of pediatric and adolescent vulvovaginitis. |
| format | Article |
| id | doaj-art-5fa4b5d4f3aa45cdaee79194950cb40a |
| institution | Kabale University |
| issn | 2287-8572 2287-8580 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj-art-5fa4b5d4f3aa45cdaee79194950cb40a2025-08-20T03:54:01ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802025-03-0168216317310.5468/ogs.242158863Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South KoreaSoo Jin Park0Ki Wook Yun1Ji Yeon Han2Sung Woo Kim3Jae Hyeon Park4Hoon Kim5Eun Hwa Choi6Seung-Yup Ku7 Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea Department of Pediatrics, Seoul National University Hospital, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea Department of Pediatrics, Seoul National University Hospital, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, KoreaObjective To analyze the microbiological and clinical characteristics of vulvovaginitis in girls, distinguishing between the premenarcheal and postmenarcheal groups in a tertiary center in South Korea. Methods This retrospective cohort study included 195 patients under 20 years of age diagnosed with vulvovaginitis at a tertiary hospital between 2014 and 2023. The patients were categorized into premenarcheal (n=95) and postmenarcheal (n=100) groups. Data on initial symptoms, microbial cultures, and treatment methods were analyzed. Results The most common initial symptom was vaginal discharge, reported in 63.1% of cases. Culture results showed a 51.3% positivity rate for any microorganism, with a prevalence of gram-negative rods (32.8%) and gram-positive cocci (14.4%). The most frequently isolated microorganisms were Escherichia coli (17.9%), Candida albicans (7.7%), and Enterococcus faecalis (6.7%). Gram-negative rods were more common in the premenarcheal group (37.1% vs. 25.0%; P=0.01). No significant differences were observed in the prevalence of gram-positive cocci and Candida species between the two groups (16.8% vs. 12.0%, P=0.22; 6.3% vs. 13.0%, P=0.09; respectively). The susceptibilities of gram-positive microorganisms to penicillin, oxacillin, clindamycin, vancomycin, and tetracycline were 58.8%, 58.3%, 94.7%, 100.0%, and 73.7%, respectively. The susceptibilities of gram-negative microorganisms to amoxicillin/clavulanic acid, ciprofloxacin, ceftriaxone, and nitrofurantoin were 89.3%, 85.3%, 76.0%, and 100.0%, respectively. Conclusion This study identified differences in the microbial profiles associated with vulvovaginitis between premenarcheal and postmenarcheal girls. Age-specific and history-based clinical approaches tailored to menarcheal status are warranted to improve the management and outcomes of pediatric and adolescent vulvovaginitis.http://www.ogscience.org/upload/pdf/ogs-24215.pdfvulvovaginitismicrobial sensitivity testsmenarcheadolescent |
| spellingShingle | Soo Jin Park Ki Wook Yun Ji Yeon Han Sung Woo Kim Jae Hyeon Park Hoon Kim Eun Hwa Choi Seung-Yup Ku Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea Obstetrics & Gynecology Science vulvovaginitis microbial sensitivity tests menarche adolescent |
| title | Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea |
| title_full | Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea |
| title_fullStr | Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea |
| title_full_unstemmed | Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea |
| title_short | Microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in South Korea |
| title_sort | microbiological and clinical characteristics of vulvovaginitis in premenarcheal and postmenarcheal girls in a tertiary center in south korea |
| topic | vulvovaginitis microbial sensitivity tests menarche adolescent |
| url | http://www.ogscience.org/upload/pdf/ogs-24215.pdf |
| work_keys_str_mv | AT soojinpark microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT kiwookyun microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT jiyeonhan microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT sungwookim microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT jaehyeonpark microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT hoonkim microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT eunhwachoi microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea AT seungyupku microbiologicalandclinicalcharacteristicsofvulvovaginitisinpremenarchealandpostmenarchealgirlsinatertiarycenterinsouthkorea |