Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury
Spinal cord injury (SCI) is a serious neurological disease, which often leads to severe impairments of motor, sensory and autonomic nervous functions. Electrical neuromodulation techniques have shown broad application prospects in the rehabilitation treatment of SCI. This study reviewed the applicat...
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Editorial Office of Rehabilitation Medicine
2024-12-01
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| Series: | 康复学报 |
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| Online Access: | http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.06015 |
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| author | LIU Wenhui SUN Wenting HU Naichong LI Yanpi WANG Zhenghui |
| author_facet | LIU Wenhui SUN Wenting HU Naichong LI Yanpi WANG Zhenghui |
| author_sort | LIU Wenhui |
| collection | DOAJ |
| description | Spinal cord injury (SCI) is a serious neurological disease, which often leads to severe impairments of motor, sensory and autonomic nervous functions. Electrical neuromodulation techniques have shown broad application prospects in the rehabilitation treatment of SCI. This study reviewed the applications and possible mechanisms of electrical neuromodulation techniques in the rehabilitation after SCI. It mainly introduced the applications of invasive techniques [spinal cord stimulation (SCS) and deep brain stimulation (DBS) ] and non-invasive techniques [peripheral nerve stimulation (PNS) and transcranial direct current stimulation (tDCS)] in the rehabilitation after SCI. The mechanisms of electrical neuromodulation techniques in the treatment of SCI may be The mechanisms of electrical neuromodulation techniques in the treatment of SCI may be related to the regulation of synaptic plasticity to promote nerve regeneration and repair, the regulation of neurotransmitter system to improve the cascade of inflammatory response, and the regulation of neural network excitability to promote the reconstruction of neural circuits. Electrical neuromodulation techniques can improve motor and autonomic nervous functions after SCI to a certain extent, but they are still unable to quickly provide the most suitable personalized treatment plans for various types of SCI; there is no consensus on the specific parameters of stimulation frequency, intensity, duration and waveform for different levels of SCI. The future research should continue to analyze the efficacy and specific mechanisms of different interventions on neurological dysfunction after SCI at different levels, and adopt multimodal and individualized regulation programs; explore the key principles of electrical signals in the recovery of motor and sensory functions after SCI, and formulate an expert consensus on the application of electrical neuromodulation techniques according to the type of spinal cord segment injury, age and gender, so as to provide a reference for the application of electrical neuromodulation techniques in the rehabilitation of patients with SCI. |
| format | Article |
| id | doaj-art-5f9ee5115a7e4f1eb0c40427a6a4befd |
| institution | OA Journals |
| issn | 2096-0328 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Rehabilitation Medicine |
| record_format | Article |
| series | 康复学报 |
| spelling | doaj-art-5f9ee5115a7e4f1eb0c40427a6a4befd2025-08-20T02:02:44ZengEditorial Office of Rehabilitation Medicine康复学报2096-03282024-12-013463364076587370Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord InjuryLIU WenhuiSUN WentingHU NaichongLI YanpiWANG ZhenghuiSpinal cord injury (SCI) is a serious neurological disease, which often leads to severe impairments of motor, sensory and autonomic nervous functions. Electrical neuromodulation techniques have shown broad application prospects in the rehabilitation treatment of SCI. This study reviewed the applications and possible mechanisms of electrical neuromodulation techniques in the rehabilitation after SCI. It mainly introduced the applications of invasive techniques [spinal cord stimulation (SCS) and deep brain stimulation (DBS) ] and non-invasive techniques [peripheral nerve stimulation (PNS) and transcranial direct current stimulation (tDCS)] in the rehabilitation after SCI. The mechanisms of electrical neuromodulation techniques in the treatment of SCI may be The mechanisms of electrical neuromodulation techniques in the treatment of SCI may be related to the regulation of synaptic plasticity to promote nerve regeneration and repair, the regulation of neurotransmitter system to improve the cascade of inflammatory response, and the regulation of neural network excitability to promote the reconstruction of neural circuits. Electrical neuromodulation techniques can improve motor and autonomic nervous functions after SCI to a certain extent, but they are still unable to quickly provide the most suitable personalized treatment plans for various types of SCI; there is no consensus on the specific parameters of stimulation frequency, intensity, duration and waveform for different levels of SCI. The future research should continue to analyze the efficacy and specific mechanisms of different interventions on neurological dysfunction after SCI at different levels, and adopt multimodal and individualized regulation programs; explore the key principles of electrical signals in the recovery of motor and sensory functions after SCI, and formulate an expert consensus on the application of electrical neuromodulation techniques according to the type of spinal cord segment injury, age and gender, so as to provide a reference for the application of electrical neuromodulation techniques in the rehabilitation of patients with SCI.http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.06015spinal cord injuryNeuromodulation techniquesElectrical stimulation therapyAxonal regenerative repairrehabilitation therapyeffect and mechanism |
| spellingShingle | LIU Wenhui SUN Wenting HU Naichong LI Yanpi WANG Zhenghui Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury 康复学报 spinal cord injury Neuromodulation techniques Electrical stimulation therapy Axonal regenerative repair rehabilitation therapy effect and mechanism |
| title | Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury |
| title_full | Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury |
| title_fullStr | Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury |
| title_full_unstemmed | Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury |
| title_short | Application and Mechanism of Electrical Neuromodulation Techniques for Rehabilitation of Spinal Cord Injury |
| title_sort | application and mechanism of electrical neuromodulation techniques for rehabilitation of spinal cord injury |
| topic | spinal cord injury Neuromodulation techniques Electrical stimulation therapy Axonal regenerative repair rehabilitation therapy effect and mechanism |
| url | http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.06015 |
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