Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.

<h4>Background</h4>Ciprofloxacin is a widely used antibiotic in medicine and agriculture. It can cause pollution to the environment and food, thereby affecting human health.<h4>Objective</h4>This study proposes the preparation of molecular imprinted fluorescent sensors and th...

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Main Authors: Shuang Li, Haijun Wang, Jinghan Wang, Feng Xu, Hongmei Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0312156
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author Shuang Li
Haijun Wang
Jinghan Wang
Feng Xu
Hongmei Li
author_facet Shuang Li
Haijun Wang
Jinghan Wang
Feng Xu
Hongmei Li
author_sort Shuang Li
collection DOAJ
description <h4>Background</h4>Ciprofloxacin is a widely used antibiotic in medicine and agriculture. It can cause pollution to the environment and food, thereby affecting human health.<h4>Objective</h4>This study proposes the preparation of molecular imprinted fluorescent sensors and their selective detection of ciprofloxacin, with the aim of achieving specific recognition and accurate detection of ciprofloxacin.<h4>Methods</h4>Rare earth metal Er3+ is added to ZnS quantum dots to prepare a molecularly imprinted fluorescence sensor (MIP/Er3+/ZnS QDs). The effects of substance concentration, pH value, and time on the fluorescence detection intensity are analyzed to determine the optimal fluorescence detection conditions.<h4>Results</h4>Experimental results showed that the sensor accurately detected ciprofloxacin with a detection limit of 31 nmol/L and the linear range of 0.1-10 μmol/L. The sensor had a recovery rate of 99.7% to 103.5% for ciprofloxacin in milk samples, with a relative standard deviation of less than 5%, indicating accurate determination of ciprofloxacin content.<h4>Conclusion</h4>Molecularly imprinted fluorescent sensors have enormous application potential in the monitoring and control of ciprofloxacin, and are of great significance for ensuring environmental and food safety.
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institution Kabale University
issn 1932-6203
language English
publishDate 2024-01-01
publisher Public Library of Science (PLoS)
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series PLoS ONE
spelling doaj-art-5f9a1acc451e45bc959fcff5aaec40592025-01-08T05:32:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011912e031215610.1371/journal.pone.0312156Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.Shuang LiHaijun WangJinghan WangFeng XuHongmei Li<h4>Background</h4>Ciprofloxacin is a widely used antibiotic in medicine and agriculture. It can cause pollution to the environment and food, thereby affecting human health.<h4>Objective</h4>This study proposes the preparation of molecular imprinted fluorescent sensors and their selective detection of ciprofloxacin, with the aim of achieving specific recognition and accurate detection of ciprofloxacin.<h4>Methods</h4>Rare earth metal Er3+ is added to ZnS quantum dots to prepare a molecularly imprinted fluorescence sensor (MIP/Er3+/ZnS QDs). The effects of substance concentration, pH value, and time on the fluorescence detection intensity are analyzed to determine the optimal fluorescence detection conditions.<h4>Results</h4>Experimental results showed that the sensor accurately detected ciprofloxacin with a detection limit of 31 nmol/L and the linear range of 0.1-10 μmol/L. The sensor had a recovery rate of 99.7% to 103.5% for ciprofloxacin in milk samples, with a relative standard deviation of less than 5%, indicating accurate determination of ciprofloxacin content.<h4>Conclusion</h4>Molecularly imprinted fluorescent sensors have enormous application potential in the monitoring and control of ciprofloxacin, and are of great significance for ensuring environmental and food safety.https://doi.org/10.1371/journal.pone.0312156
spellingShingle Shuang Li
Haijun Wang
Jinghan Wang
Feng Xu
Hongmei Li
Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
PLoS ONE
title Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
title_full Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
title_fullStr Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
title_full_unstemmed Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
title_short Preparation of molecular imprinted fluorescence sensor based on Er3+/ZnS QDs and its selective detection of ciprofloxacin in various matrices.
title_sort preparation of molecular imprinted fluorescence sensor based on er3 zns qds and its selective detection of ciprofloxacin in various matrices
url https://doi.org/10.1371/journal.pone.0312156
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AT fengxu preparationofmolecularimprintedfluorescencesensorbasedoner3znsqdsanditsselectivedetectionofciprofloxacininvariousmatrices
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