Hyperacute Rejection of a Living Unrelated Kidney Graft
We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation,...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/613641 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552644119363584 |
|---|---|
| author | Dietlind Tittelbach-Helmrich Dirk Bausch Oliver Drognitz Heike Goebel Christian Schulz-Huotari Albrecht Kramer-Zucker Ulrich Theodor Hopt Przemyslaw Pisarski |
| author_facet | Dietlind Tittelbach-Helmrich Dirk Bausch Oliver Drognitz Heike Goebel Christian Schulz-Huotari Albrecht Kramer-Zucker Ulrich Theodor Hopt Przemyslaw Pisarski |
| author_sort | Dietlind Tittelbach-Helmrich |
| collection | DOAJ |
| description | We present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation, resulted positive. During surgery no abnormalities occurred. Four hours after the transplantation diuresis suddenly decreased. In an immediately performed relaparotomy the transplanted kidney showed signs of hyperacute rejection and had to be removed. Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. We recommend examining more closely recipients of second allografts, considering not only a positive T-cell crossmatch but also a positive B-cell crossmatch as exclusion criteria for transplantation. |
| format | Article |
| id | doaj-art-5f9a16c7d5484a2e8aa65b950d0bce35 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-5f9a16c7d5484a2e8aa65b950d0bce352025-02-03T05:58:13ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/613641613641Hyperacute Rejection of a Living Unrelated Kidney GraftDietlind Tittelbach-Helmrich0Dirk Bausch1Oliver Drognitz2Heike Goebel3Christian Schulz-Huotari4Albrecht Kramer-Zucker5Ulrich Theodor Hopt6Przemyslaw Pisarski7Department of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyDepartment of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyDepartment of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyInstitute of Pathology, University of Freiburg, Breisacher Straße 115a, 79106 Freiburg im Breisgau, GermanyDepartment of Transfusion Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyDepartment of Nephrology, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyDepartment of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyDepartment of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg im Breisgau, GermanyWe present a case report of a 59-year-old man, who received a blood group identical living unrelated kidney graft. This was his second kidney transplantation. Pretransplant T-cell crossmatch resulted negative. B-cell crossmatch, which is not considered a strict contraindication for transplantation, resulted positive. During surgery no abnormalities occurred. Four hours after the transplantation diuresis suddenly decreased. In an immediately performed relaparotomy the transplanted kidney showed signs of hyperacute rejection and had to be removed. Pathological examination was consistent with hyperacute rejection. Depositions of IgM or IgG antibodies were not present in pathologic evaluation of the rejected kidney, suggesting that no irregular endothelial specific antibodies had been involved in the rejection. We recommend examining more closely recipients of second allografts, considering not only a positive T-cell crossmatch but also a positive B-cell crossmatch as exclusion criteria for transplantation.http://dx.doi.org/10.1155/2014/613641 |
| spellingShingle | Dietlind Tittelbach-Helmrich Dirk Bausch Oliver Drognitz Heike Goebel Christian Schulz-Huotari Albrecht Kramer-Zucker Ulrich Theodor Hopt Przemyslaw Pisarski Hyperacute Rejection of a Living Unrelated Kidney Graft Case Reports in Medicine |
| title | Hyperacute Rejection of a Living Unrelated Kidney Graft |
| title_full | Hyperacute Rejection of a Living Unrelated Kidney Graft |
| title_fullStr | Hyperacute Rejection of a Living Unrelated Kidney Graft |
| title_full_unstemmed | Hyperacute Rejection of a Living Unrelated Kidney Graft |
| title_short | Hyperacute Rejection of a Living Unrelated Kidney Graft |
| title_sort | hyperacute rejection of a living unrelated kidney graft |
| url | http://dx.doi.org/10.1155/2014/613641 |
| work_keys_str_mv | AT dietlindtittelbachhelmrich hyperacuterejectionofalivingunrelatedkidneygraft AT dirkbausch hyperacuterejectionofalivingunrelatedkidneygraft AT oliverdrognitz hyperacuterejectionofalivingunrelatedkidneygraft AT heikegoebel hyperacuterejectionofalivingunrelatedkidneygraft AT christianschulzhuotari hyperacuterejectionofalivingunrelatedkidneygraft AT albrechtkramerzucker hyperacuterejectionofalivingunrelatedkidneygraft AT ulrichtheodorhopt hyperacuterejectionofalivingunrelatedkidneygraft AT przemyslawpisarski hyperacuterejectionofalivingunrelatedkidneygraft |