(−)‐Epicatechin Rescues Memory Deficits by Activation of Autophagy in a Mouse Model of Tauopathies

(−)‐Epicatechin Rescues Memory Deficits by Activation of Autophagy in a Mouse Model of Tauopathies

ABSTRACT In tauopathies, defects in autophagy‐lysosomal protein degradation are thought to contribute to the abnormal accumulation of aggregated tau. Recent studies have shown that (−)‐Epicatechin (Epi), a dietary flavonoid belonging to the flavan‐3‐ol subgroup, improves blood flow, modulates metabo...

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Bibliographic Details
Main Authors: Yanqing Wu, Ting Li, Xingjun Jiang, Jianmin Ling, Zaihua Zhao, Jiahui Zhu, Chongyang Chen, Qian Liu, Xifei Yang, Xuefeng Shen, Rong Ma, Gang Li, Gongping Liu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:MedComm
Subjects:
autophagy
(−)‐Epicatechin
FTDP
memory deficits
tauopathies
Online Access:https://doi.org/10.1002/mco2.70144
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