Potentially actionable molecular alterations in particular related to poor oncologic outcomes in salivary gland carcinomas

Potentially actionable molecular alterations in particular related to poor oncologic outcomes in salivary gland carcinomas

Abstract Aim The study was designed to evaluate molecular alterations, relevant to the prognosis and personalized therapy of salivary gland cancers (SGCs). Materials and methods DNA was extracted from archival tissue of 40 patients with various SGCs subtypes. A targeted next-generation sequencing (N...

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Bibliographic Details
Main Authors: Julia Pikul, Marcin M. Machnicki, Anna Rzepakowska, Natalia Winiarska, Agnieszka Chudy, Albert Moskowicz, Kacper Król, Łukasz Fus, Grażyna Kostrzewa, Tomasz Stokłosa
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Salivary gland cancer
Next-generation sequencing
Genetic analysis
Mutational landscape
Targeted therapy
Precision oncology
Online Access:https://doi.org/10.1186/s12885-024-13421-0
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