Obstructive sleep apnea and structural and functional brain alterations: a brain-wide investigation from clinical association to genetic causality

Obstructive sleep apnea and structural and functional brain alterations: a brain-wide investigation from clinical association to genetic causality

Abstract Background Obstructive sleep apnea (OSA) is linked to brain alterations, but the specific regions affected and the causal associations between these changes remain unclear. Methods We studied 20 pairs of age-, sex-, BMI-, and education- matched OSA patients and healthy controls using multim...

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Bibliographic Details
Main Authors: Kang Wu, Qiming Gan, Yuhong Pi, Yanjuan Wu, Wenjin Zou, Xiaofen Su, Sun Zhang, Xinni Wang, Xinchun Li, Nuofu Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medicine
Subjects:
Obstructive sleep apnea
Brain structure and function
Neuroimaging
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-025-03876-8
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