Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence

Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B...

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Main Authors: Suneel Kumar Garg, Omender Singh, Deven Juneja, Niraj Tyagi, Amandeep Singh Khurana, Amit Qamra, Salman Motlekar, Hanmant Barkate
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2017/3635609
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author Suneel Kumar Garg
Omender Singh
Deven Juneja
Niraj Tyagi
Amandeep Singh Khurana
Amit Qamra
Salman Motlekar
Hanmant Barkate
author_facet Suneel Kumar Garg
Omender Singh
Deven Juneja
Niraj Tyagi
Amandeep Singh Khurana
Amit Qamra
Salman Motlekar
Hanmant Barkate
author_sort Suneel Kumar Garg
collection DOAJ
description Polymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B in Gram-negative infections with update on its pharmacology.
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institution Kabale University
issn 2090-1305
2090-1313
language English
publishDate 2017-01-01
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record_format Article
series Critical Care Research and Practice
spelling doaj-art-5f6f7e62724c4a928de07488b41656ad2025-02-03T01:27:40ZengWileyCritical Care Research and Practice2090-13052090-13132017-01-01201710.1155/2017/36356093635609Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current EvidenceSuneel Kumar Garg0Omender Singh1Deven Juneja2Niraj Tyagi3Amandeep Singh Khurana4Amit Qamra5Salman Motlekar6Hanmant Barkate7Institute of Critical Care Medicine, Max Super Specialty Hospital, Saket, New Delhi 110017, IndiaInstitute of Critical Care Medicine, Max Super Specialty Hospital, Saket, New Delhi 110017, IndiaInstitute of Critical Care Medicine, Max Super Specialty Hospital, Saket, New Delhi 110017, IndiaDepartment of Critical Care and Emergency Medicine, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, IndiaDepartment of Medical Affairs, Wockhardt Ltd., Wockhardt Towers, Mumbai 400051, IndiaDepartment of Medical Affairs, Wockhardt Ltd., Wockhardt Towers, Mumbai 400051, IndiaDepartment of Medical Affairs, Wockhardt Ltd., Wockhardt Towers, Mumbai 400051, IndiaDepartment of Medical Affairs, Wockhardt Ltd., Wockhardt Towers, Mumbai 400051, IndiaPolymyxin B has resurged in recent years as a last resort therapy for Gram-negative multidrug-resistant (MDR) and extremely drug resistant (XDR) infections. Understanding newer evidence on polymyxin B is necessary to guide clinical decision making. Here, we present a literature review of polymyxin B in Gram-negative infections with update on its pharmacology.http://dx.doi.org/10.1155/2017/3635609
spellingShingle Suneel Kumar Garg
Omender Singh
Deven Juneja
Niraj Tyagi
Amandeep Singh Khurana
Amit Qamra
Salman Motlekar
Hanmant Barkate
Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
Critical Care Research and Practice
title Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_full Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_fullStr Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_full_unstemmed Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_short Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence
title_sort resurgence of polymyxin b for mdr xdr gram negative infections an overview of current evidence
url http://dx.doi.org/10.1155/2017/3635609
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