Hepatitis B Reactivation Following COVID-19
We describe the case of a 83-year-old man who received an allogenic stem cell transplant for acute myelogenous leukemia in 2010. He developed mild COVID-19 illness in 2023 and improved without corticosteroids. Elevated serum transaminase levels were noted, with subsequent evaluation showing a hepati...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2024-11-01
|
| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0253 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849698827153440768 |
|---|---|
| author | Mehakmeet Bhatia Pranatharthi Chandrasekar |
| author_facet | Mehakmeet Bhatia Pranatharthi Chandrasekar |
| author_sort | Mehakmeet Bhatia |
| collection | DOAJ |
| description | We describe the case of a 83-year-old man who received an allogenic stem cell transplant for acute myelogenous leukemia in 2010. He developed mild COVID-19 illness in 2023 and improved without corticosteroids. Elevated serum transaminase levels were noted, with subsequent evaluation showing a hepatitis B virus (HBV) DNA level measured by polymerase chain reaction of 297 000 000 IU/mL, and positive hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B core antibody (anti-HBc). At baseline, he had a positive anti-HBc and a negative HBsAg. He was treated with entecavir and showed improvement in HBV DNA polymerase chain reaction and serum transaminase levels. Patients with COVID-19 who have persistently elevated serum transaminase levels should be evaluated for HBV reactivation. |
| format | Article |
| id | doaj-art-5f6d4da74f6d4d05b993ad78b4f5d033 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-5f6d4da74f6d4d05b993ad78b4f5d0332025-08-20T03:18:48ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-11-0131110.7326/aimcc.2024.0253Hepatitis B Reactivation Following COVID-19Mehakmeet Bhatia0Pranatharthi Chandrasekar11School of Medicine, Division of Infectious Diseases, Wayne State University, Detroit, Michigan1School of Medicine, Division of Infectious Diseases, Wayne State University, Detroit, MichiganWe describe the case of a 83-year-old man who received an allogenic stem cell transplant for acute myelogenous leukemia in 2010. He developed mild COVID-19 illness in 2023 and improved without corticosteroids. Elevated serum transaminase levels were noted, with subsequent evaluation showing a hepatitis B virus (HBV) DNA level measured by polymerase chain reaction of 297 000 000 IU/mL, and positive hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), and hepatitis B core antibody (anti-HBc). At baseline, he had a positive anti-HBc and a negative HBsAg. He was treated with entecavir and showed improvement in HBV DNA polymerase chain reaction and serum transaminase levels. Patients with COVID-19 who have persistently elevated serum transaminase levels should be evaluated for HBV reactivation.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0253 |
| spellingShingle | Mehakmeet Bhatia Pranatharthi Chandrasekar Hepatitis B Reactivation Following COVID-19 Annals of Internal Medicine: Clinical Cases |
| title | Hepatitis B Reactivation Following COVID-19 |
| title_full | Hepatitis B Reactivation Following COVID-19 |
| title_fullStr | Hepatitis B Reactivation Following COVID-19 |
| title_full_unstemmed | Hepatitis B Reactivation Following COVID-19 |
| title_short | Hepatitis B Reactivation Following COVID-19 |
| title_sort | hepatitis b reactivation following covid 19 |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0253 |
| work_keys_str_mv | AT mehakmeetbhatia hepatitisbreactivationfollowingcovid19 AT pranatharthichandrasekar hepatitisbreactivationfollowingcovid19 |