THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)

In this article the necessity of working out of individual therapeutical immunosuppressive tactics was consi- dered. The authors believe that doses and schemes of used drugs must not prevent the immunity regulation. Immunosuppressive drugs must induce native mechanisms of immune tolerance and repara...

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Main Authors: S. D. Artamonov, D. A. Velikiy, N. A. Onischenko, M. E. Krasheninnikov, I. M. Ivanov, L. V. Bashkina, A. O. Nikolskaya
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-05-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/169
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author S. D. Artamonov
D. A. Velikiy
N. A. Onischenko
M. E. Krasheninnikov
I. M. Ivanov
L. V. Bashkina
A. O. Nikolskaya
author_facet S. D. Artamonov
D. A. Velikiy
N. A. Onischenko
M. E. Krasheninnikov
I. M. Ivanov
L. V. Bashkina
A. O. Nikolskaya
author_sort S. D. Artamonov
collection DOAJ
description In this article the necessity of working out of individual therapeutical immunosuppressive tactics was consi- dered. The authors believe that doses and schemes of used drugs must not prevent the immunity regulation. Immunosuppressive drugs must induce native mechanisms of immune tolerance and reparative regeneration for preventing of fibrotic processes in grafts (liver). For optimal effect of drug immunosuppression after clinical liver transplantation it was suggested to reveal tole- rogenic recipient’s groups and also to work out and use informative diagnostic and prognostic methods for value of individual level and power tolerance stability of recipients.
format Article
id doaj-art-5f6b0ad3ceb34f98ac32d0706e7a45cf
institution Kabale University
issn 1995-1191
language Russian
publishDate 2012-05-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-5f6b0ad3ceb34f98ac32d0706e7a45cf2025-08-20T03:44:23ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912012-05-011429810910.15825/1995-1191-2012-2-98-109112THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)S. D. Artamonov0D. A. Velikiy1N. A. Onischenko2M. E. Krasheninnikov3I. M. Ivanov4L. V. Bashkina5A. O. Nikolskaya6Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowIn this article the necessity of working out of individual therapeutical immunosuppressive tactics was consi- dered. The authors believe that doses and schemes of used drugs must not prevent the immunity regulation. Immunosuppressive drugs must induce native mechanisms of immune tolerance and reparative regeneration for preventing of fibrotic processes in grafts (liver). For optimal effect of drug immunosuppression after clinical liver transplantation it was suggested to reveal tole- rogenic recipient’s groups and also to work out and use informative diagnostic and prognostic methods for value of individual level and power tolerance stability of recipients.https://journal.transpl.ru/vtio/article/view/169immunosuppressive therapytolerancefibrosis at liver transplantation.
spellingShingle S. D. Artamonov
D. A. Velikiy
N. A. Onischenko
M. E. Krasheninnikov
I. M. Ivanov
L. V. Bashkina
A. O. Nikolskaya
THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
Вестник трансплантологии и искусственных органов
immunosuppressive therapy
tolerance
fibrosis at liver transplantation.
title THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
title_full THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
title_fullStr THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
title_full_unstemmed THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
title_short THE MODERN IMMUNOSUPPRESSIVE TACTICS AS A WAY FOR INDUCING OF TOLEROGENIC STRATEGY AFTER LIVER TRANSPLANTATION (ANALYSIS OF THE PROBLEM STATUS)
title_sort modern immunosuppressive tactics as a way for inducing of tolerogenic strategy after liver transplantation analysis of the problem status
topic immunosuppressive therapy
tolerance
fibrosis at liver transplantation.
url https://journal.transpl.ru/vtio/article/view/169
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