The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients

Purpose. To compare the prevalence of and factors associated with Demodex brevis and Demodex folliculorum in patients with cylindrical dandruff (CD group) and healthy controls. Methods. Eyelashes were taken from 1680 patients with CD and 1700 healthy controls in China from March 2015 to May 2017. Al...

Full description

Saved in:
Bibliographic Details
Main Authors: Jing Zhong, Yiwei Tan, Saiqun Li, Lulu Peng, Bowen Wang, Yuqing Deng, Jin Yuan
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/8949683
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850120533049344000
author Jing Zhong
Yiwei Tan
Saiqun Li
Lulu Peng
Bowen Wang
Yuqing Deng
Jin Yuan
author_facet Jing Zhong
Yiwei Tan
Saiqun Li
Lulu Peng
Bowen Wang
Yuqing Deng
Jin Yuan
author_sort Jing Zhong
collection DOAJ
description Purpose. To compare the prevalence of and factors associated with Demodex brevis and Demodex folliculorum in patients with cylindrical dandruff (CD group) and healthy controls. Methods. Eyelashes were taken from 1680 patients with CD and 1700 healthy controls in China from March 2015 to May 2017. All patients underwent a complete eye examination, and Demodex spp. were counted. The prevalence was analyzed according to age, gender, and clinical features. Results. Mean patient age was 42.93 ± 16.52 (3–88) and 39.4 ± 13.6 (7–81) years old in the CD and healthy control groups, respectively. In the CD and healthy groups, the positive rate for Demodex folliculorum was 27.92% and 8.47%, respectively, while that for Demodex brevis was 31.67% and 6.65%, respectively. In the CD group, the prevalence of Demodex brevis was higher than that of Demodex folliculorum, no matter in the females (33.65% versus 29.01%) or the males (28.54% versus 23.88%) in the CD group. Moreover, the numbers of Demodex folliculorum and Demodex brevis were significantly and positively correlated with age, in both children and old patients (both P<0.001), as well as with the severity of eyelid congestion (all P<0.05). Conclusions. In a large sample population, the prevalence of Demodex brevis and Demodex folliculorum was higher in the CD group than in healthy volunteers. In addition, the severity of eyelid congestion might be exacerbated by the number of Demodex spp., which may therefore provide a good clinical reference and objective guide.
format Article
id doaj-art-5f5b985302194a08958b9ef794ea23b8
institution OA Journals
issn 2090-004X
2090-0058
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Journal of Ophthalmology
spelling doaj-art-5f5b985302194a08958b9ef794ea23b82025-08-20T02:35:21ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/89496838949683The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff PatientsJing Zhong0Yiwei Tan1Saiqun Li2Lulu Peng3Bowen Wang4Yuqing Deng5Jin Yuan6State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510064, ChinaPurpose. To compare the prevalence of and factors associated with Demodex brevis and Demodex folliculorum in patients with cylindrical dandruff (CD group) and healthy controls. Methods. Eyelashes were taken from 1680 patients with CD and 1700 healthy controls in China from March 2015 to May 2017. All patients underwent a complete eye examination, and Demodex spp. were counted. The prevalence was analyzed according to age, gender, and clinical features. Results. Mean patient age was 42.93 ± 16.52 (3–88) and 39.4 ± 13.6 (7–81) years old in the CD and healthy control groups, respectively. In the CD and healthy groups, the positive rate for Demodex folliculorum was 27.92% and 8.47%, respectively, while that for Demodex brevis was 31.67% and 6.65%, respectively. In the CD group, the prevalence of Demodex brevis was higher than that of Demodex folliculorum, no matter in the females (33.65% versus 29.01%) or the males (28.54% versus 23.88%) in the CD group. Moreover, the numbers of Demodex folliculorum and Demodex brevis were significantly and positively correlated with age, in both children and old patients (both P<0.001), as well as with the severity of eyelid congestion (all P<0.05). Conclusions. In a large sample population, the prevalence of Demodex brevis and Demodex folliculorum was higher in the CD group than in healthy volunteers. In addition, the severity of eyelid congestion might be exacerbated by the number of Demodex spp., which may therefore provide a good clinical reference and objective guide.http://dx.doi.org/10.1155/2019/8949683
spellingShingle Jing Zhong
Yiwei Tan
Saiqun Li
Lulu Peng
Bowen Wang
Yuqing Deng
Jin Yuan
The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
Journal of Ophthalmology
title The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
title_full The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
title_fullStr The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
title_full_unstemmed The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
title_short The Prevalence of Demodex folliculorum and Demodex brevis in Cylindrical Dandruff Patients
title_sort prevalence of demodex folliculorum and demodex brevis in cylindrical dandruff patients
url http://dx.doi.org/10.1155/2019/8949683
work_keys_str_mv AT jingzhong theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT yiweitan theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT saiqunli theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT lulupeng theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT bowenwang theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT yuqingdeng theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT jinyuan theprevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT jingzhong prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT yiweitan prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT saiqunli prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT lulupeng prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT bowenwang prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT yuqingdeng prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients
AT jinyuan prevalenceofdemodexfolliculorumanddemodexbrevisincylindricaldandruffpatients