Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis
Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis. Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis. Methods: A descriptive, uncontrolled study was performed in...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Spanish |
| Published: |
ECIMED
2023-05-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2728 |
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| Summary: | Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis.
Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis.
Methods: A descriptive, uncontrolled study was performed in 260 elderly patients at risk of deep vein thrombosis. All patients underwent quantitative D-dimer assay.
Results: The D-dimer concentration of patients with deep venous thrombosis had a median of 3106.5 ng/ml and was about 1.5 times higher than that of patients without deep venous thrombosis. With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity of the method is low (16.51%), but the sensitivity is high (100%). And the positive predictive value is low (18.75%) but the negative predictive value is absolute (100%).
Conclusion: With a threshold of D-dimer concentration of 500 ng/mL to determine deep venous thrombosis, the specificity and positive predictive value of the method are low, but the sensitivity and negative predictive value are high. |
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| ISSN: | 1561-3046 |