Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients

Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients

Introduction: Cellular senescence is the irreversible growth arrest subsequent to oncogenic mutations, DNA damage, or metabolic insult. Senescence is associated with ageing and chronic age associated diseases such as cardiovascular disease and diabetes. The involvement of cellular senescence in acut...

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Main Authors: Sean McCallion, Thomas McLarnon, Eamonn Cooper, Andrew R. English, Steven Watterson, Melody El Chemaly, Cathy McGeough, Amanda Eakin, Tan Ahmed, Philip Gardiner, Adrian Pendleton, Gary Wright, Declan McGuigan, Maurice O’Kane, Aaron Peace, Ying Kuan, David S. Gibson, Paula L. McClean, Catriona Kelly, Victoria McGilligan, Elaine K. Murray, Frank McCarroll, Anthony J. Bjourson, Taranjit Singh Rai
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Cells
Subjects:
senescence
chronic kidney disease
acute kidney injury
biomarker
machine learning
Online Access:https://www.mdpi.com/2073-4409/13/19/1613
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