Primary Breast Osteosarcoma: A Case Report and Literature Review
Primary breast osteosarcomas are rare. We report an unusual case of a 58-year-old female presenting with a right breast lump for 1 month. Mammography showed an ill-defined, heterogeneous, and coarse calcification measuring 4 cm over the upper inner quadrant of the right breast. She received an upfro...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Cancer Research and Practice |
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| Online Access: | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00012 |
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| _version_ | 1841549926239043584 |
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| author | Tsung-Han Tsai Hsuan-Ying Huang Yu-Li Su |
| author_facet | Tsung-Han Tsai Hsuan-Ying Huang Yu-Li Su |
| author_sort | Tsung-Han Tsai |
| collection | DOAJ |
| description | Primary breast osteosarcomas are rare. We report an unusual case of a 58-year-old female presenting with a right breast lump for 1 month. Mammography showed an ill-defined, heterogeneous, and coarse calcification measuring 4 cm over the upper inner quadrant of the right breast. She received an upfront partial mastectomy after core needle biopsy showed osteoid-like tissue with the presence of atypical cells and some multinucleated giant cells. The final pathology revealed Grade 3 extraosseous osteosarcoma, osteoblastic type. Four cycles of adjuvant doxorubicin and cisplatin followed by radiotherapy were given due to the close surgical margin. She has since been free of recurrence for 3 years. |
| format | Article |
| id | doaj-art-5f36f7bc39c14ce18539716c89025619 |
| institution | Kabale University |
| issn | 2311-3006 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj-art-5f36f7bc39c14ce18539716c890256192025-01-10T12:28:06ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062024-12-0111414414710.4103/ejcrp.eJCRP-D-24-00012Primary Breast Osteosarcoma: A Case Report and Literature ReviewTsung-Han TsaiHsuan-Ying HuangYu-Li SuPrimary breast osteosarcomas are rare. We report an unusual case of a 58-year-old female presenting with a right breast lump for 1 month. Mammography showed an ill-defined, heterogeneous, and coarse calcification measuring 4 cm over the upper inner quadrant of the right breast. She received an upfront partial mastectomy after core needle biopsy showed osteoid-like tissue with the presence of atypical cells and some multinucleated giant cells. The final pathology revealed Grade 3 extraosseous osteosarcoma, osteoblastic type. Four cycles of adjuvant doxorubicin and cisplatin followed by radiotherapy were given due to the close surgical margin. She has since been free of recurrence for 3 years.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00012case reportextraosseous osteossarcomaprimary breast osteosarcoma |
| spellingShingle | Tsung-Han Tsai Hsuan-Ying Huang Yu-Li Su Primary Breast Osteosarcoma: A Case Report and Literature Review Journal of Cancer Research and Practice case report extraosseous osteossarcoma primary breast osteosarcoma |
| title | Primary Breast Osteosarcoma: A Case Report and Literature Review |
| title_full | Primary Breast Osteosarcoma: A Case Report and Literature Review |
| title_fullStr | Primary Breast Osteosarcoma: A Case Report and Literature Review |
| title_full_unstemmed | Primary Breast Osteosarcoma: A Case Report and Literature Review |
| title_short | Primary Breast Osteosarcoma: A Case Report and Literature Review |
| title_sort | primary breast osteosarcoma a case report and literature review |
| topic | case report extraosseous osteossarcoma primary breast osteosarcoma |
| url | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00012 |
| work_keys_str_mv | AT tsunghantsai primarybreastosteosarcomaacasereportandliteraturereview AT hsuanyinghuang primarybreastosteosarcomaacasereportandliteraturereview AT yulisu primarybreastosteosarcomaacasereportandliteraturereview |