Decoding glycosylation in cardiovascular diseases: mechanisms, biomarkers, and therapeutic opportunities
Protein glycosylation, particularly O-GlcNAcylation, is a critical post-translational modification (PTM) that regulates cardiac and vascular functions by modulating protein stability, localization, and interactions. Dysregulated glycosylation is generally believed as a key driver in the pathogenesis...
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| Main Authors: | Gang Li, Kaidi Ren, Yage Jin, Yang Yang, Yi Luan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1570158/full |
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