Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria
Homocystinuria is a rare autosomal recessive metabolic disorder due to a defect in the cystathionine β-synthase (CBS) that leads to high homocysteine plasma levels. Psychiatric symptoms secondary to homocystinuria have been described in the literature; however, there is a lack of information about o...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2021/5523453 |
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| _version_ | 1832564888690491392 |
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| author | Vera Froes Hugo Afonso Zita Gameiro |
| author_facet | Vera Froes Hugo Afonso Zita Gameiro |
| author_sort | Vera Froes |
| collection | DOAJ |
| description | Homocystinuria is a rare autosomal recessive metabolic disorder due to a defect in the cystathionine β-synthase (CBS) that leads to high homocysteine plasma levels. Psychiatric symptoms secondary to homocystinuria have been described in the literature; however, there is a lack of information about obsessive-compulsive symptoms correlated to this disorder. We describe the case of a 39 years old man, diagnosed with homocystinuria in childhood, with no previous psychiatric history that presented obsessive-compulsive disorder (OCD) like symptoms, as a manifestation of homocystinuria. This case underlines the importance for a psychiatrist to explore medical nonpsychiatric history, especially when presentation is abrupt, atypical, or in treatment-resistant cases. |
| format | Article |
| id | doaj-art-5f1d69bc5a8a4d9b8adada997ed8330f |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-5f1d69bc5a8a4d9b8adada997ed8330f2025-02-03T01:09:56ZengWileyCase Reports in Psychiatry2090-682X2090-68382021-01-01202110.1155/2021/55234535523453Obsessive-Compulsive Symptoms as a Manifestation of HomocystinuriaVera Froes0Hugo Afonso1Zita Gameiro2Centro Hospitalar Barreiro Montijo, Barreiro, PortugalCentro Hospitalar Tondela Viseu, Viseu, PortugalCentro Hospitalar Barreiro Montijo, Barreiro, PortugalHomocystinuria is a rare autosomal recessive metabolic disorder due to a defect in the cystathionine β-synthase (CBS) that leads to high homocysteine plasma levels. Psychiatric symptoms secondary to homocystinuria have been described in the literature; however, there is a lack of information about obsessive-compulsive symptoms correlated to this disorder. We describe the case of a 39 years old man, diagnosed with homocystinuria in childhood, with no previous psychiatric history that presented obsessive-compulsive disorder (OCD) like symptoms, as a manifestation of homocystinuria. This case underlines the importance for a psychiatrist to explore medical nonpsychiatric history, especially when presentation is abrupt, atypical, or in treatment-resistant cases.http://dx.doi.org/10.1155/2021/5523453 |
| spellingShingle | Vera Froes Hugo Afonso Zita Gameiro Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria Case Reports in Psychiatry |
| title | Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria |
| title_full | Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria |
| title_fullStr | Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria |
| title_full_unstemmed | Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria |
| title_short | Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria |
| title_sort | obsessive compulsive symptoms as a manifestation of homocystinuria |
| url | http://dx.doi.org/10.1155/2021/5523453 |
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