Combined stimuli of elasticity and microgrooves form aligned myotubes that characterize slow twitch muscles
Abstract Skeletal muscles are classified into slow-twitch muscles composed primarily of type I and IIa fibers with high oxidative metabolism, and fast-twitch muscles composed of type IIx and IIb fibers with high glycolytic metabolism. Fiber-type shifts occur during development and aging; however, th...
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| Main Authors: | Hiroki Hamaguchi, Tomoko G. Oyama, Kotaro Oyama, Yasuko Manabe, Nobuharu L. Fujii, Mitsumasa Taguchi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-12744-7 |
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