Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis

An important goal for the surgeon after performing proctocolectomy for ulcerative colitis is the preservation of continence, with the formation of a pelvic ileal pouch. In most patients who have required this procedure, clinical results have been satisfactory. In recent years, it has become appr...

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Main Author: Hugh J Freeman
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2001/713823
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author Hugh J Freeman
author_facet Hugh J Freeman
author_sort Hugh J Freeman
collection DOAJ
description An important goal for the surgeon after performing proctocolectomy for ulcerative colitis is the preservation of continence, with the formation of a pelvic ileal pouch. In most patients who have required this procedure, clinical results have been satisfactory. In recent years, it has become appreciated that many patients with a satisfactory surgical result are still at risk for pouchitis and pouch neoplasia. This is not surprising because creation of a pouch leads to an environment characterized by stasis, with associated mucosal adaptive changes. In some patients, the ileal mucosa in the pouch may assume the appearance of colonic mucosa.
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spelling doaj-art-5f0fa0fbe60643088d42d20c6d3d90102025-08-20T03:34:22ZengWileyCanadian Journal of Gastroenterology0835-79002001-01-01151177477510.1155/2001/713823Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative ColitisHugh J Freeman0Department of Medicine (Gastroenterology), University of British Columbia Hospital, Vancouver, British Columbia, CanadaAn important goal for the surgeon after performing proctocolectomy for ulcerative colitis is the preservation of continence, with the formation of a pelvic ileal pouch. In most patients who have required this procedure, clinical results have been satisfactory. In recent years, it has become appreciated that many patients with a satisfactory surgical result are still at risk for pouchitis and pouch neoplasia. This is not surprising because creation of a pouch leads to an environment characterized by stasis, with associated mucosal adaptive changes. In some patients, the ileal mucosa in the pouch may assume the appearance of colonic mucosa.http://dx.doi.org/10.1155/2001/713823
spellingShingle Hugh J Freeman
Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
Canadian Journal of Gastroenterology
title Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
title_full Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
title_fullStr Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
title_full_unstemmed Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
title_short Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis
title_sort dysplasia risk in ileal pouches after reconstructive surgery for ulcerative colitis
url http://dx.doi.org/10.1155/2001/713823
work_keys_str_mv AT hughjfreeman dysplasiariskinilealpouchesafterreconstructivesurgeryforulcerativecolitis