Dysplasia Risk in Ileal Pouches after Reconstructive Surgery for Ulcerative Colitis

An important goal for the surgeon after performing proctocolectomy for ulcerative colitis is the preservation of continence, with the formation of a pelvic ileal pouch. In most patients who have required this procedure, clinical results have been satisfactory. In recent years, it has become appr...

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Bibliographic Details
Main Author: Hugh J Freeman
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2001/713823
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Summary:An important goal for the surgeon after performing proctocolectomy for ulcerative colitis is the preservation of continence, with the formation of a pelvic ileal pouch. In most patients who have required this procedure, clinical results have been satisfactory. In recent years, it has become appreciated that many patients with a satisfactory surgical result are still at risk for pouchitis and pouch neoplasia. This is not surprising because creation of a pouch leads to an environment characterized by stasis, with associated mucosal adaptive changes. In some patients, the ileal mucosa in the pouch may assume the appearance of colonic mucosa.
ISSN:0835-7900