Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy
Abstract The magnetic quantum phenomena triggered by electrons in carbon-based materials are challenging to decipher and exploit, thus sparking extensive research interest. Carbon quantum dots (CQDs), emerging candidates in nanomedicine, exhibit fascinating behaviors related to electron spin, relaxa...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60951-7 |
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| _version_ | 1849334610544033792 |
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| author | Tesen Zhang Quansheng Cheng Hongwei Cheng Qingcheng Wang Bingzhe Wang Bohan Zhang Handong Sun Chuxia Deng Zikang Tang |
| author_facet | Tesen Zhang Quansheng Cheng Hongwei Cheng Qingcheng Wang Bingzhe Wang Bohan Zhang Handong Sun Chuxia Deng Zikang Tang |
| author_sort | Tesen Zhang |
| collection | DOAJ |
| description | Abstract The magnetic quantum phenomena triggered by electrons in carbon-based materials are challenging to decipher and exploit, thus sparking extensive research interest. Carbon quantum dots (CQDs), emerging candidates in nanomedicine, exhibit fascinating behaviors related to electron spin, relaxation, and migration. Herein, we report a magnetic edge state structure within nonmetallic CQDs that generates nitrogen hyperfine splitting at room temperature. Furthermore, a series of near-infrared (NIR) absorption bandgaps are produced based on spin–orbit coupling and dipole–dipole interactions, exhibiting potential in photothermal and thermoelectric catalysis. By modulating the surface ligands and solvent, relaxation rates are accelerated through spin averaging, which results in CQDs serving as desirable T1 contrast agents with the highest relaxivity for magnetic resonance imaging (MRI) and NIR-II cancer therapy agents. Combining these characteristics, we propose an MRI-guided approach to precision cancer therapy that offers a pathway for the rapid advancement of nanomedicine. |
| format | Article |
| id | doaj-art-5f0877739b144fe6becb089fe2a47b26 |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-5f0877739b144fe6becb089fe2a47b262025-08-20T03:45:31ZengNature PortfolioNature Communications2041-17232025-07-0116111110.1038/s41467-025-60951-7Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapyTesen Zhang0Quansheng Cheng1Hongwei Cheng2Qingcheng Wang3Bingzhe Wang4Bohan Zhang5Handong Sun6Chuxia Deng7Zikang Tang8Institute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauFaculty of Health Sciences, University of MacauInstitute of Applied Physics and Materials Engineering, University of MacauAbstract The magnetic quantum phenomena triggered by electrons in carbon-based materials are challenging to decipher and exploit, thus sparking extensive research interest. Carbon quantum dots (CQDs), emerging candidates in nanomedicine, exhibit fascinating behaviors related to electron spin, relaxation, and migration. Herein, we report a magnetic edge state structure within nonmetallic CQDs that generates nitrogen hyperfine splitting at room temperature. Furthermore, a series of near-infrared (NIR) absorption bandgaps are produced based on spin–orbit coupling and dipole–dipole interactions, exhibiting potential in photothermal and thermoelectric catalysis. By modulating the surface ligands and solvent, relaxation rates are accelerated through spin averaging, which results in CQDs serving as desirable T1 contrast agents with the highest relaxivity for magnetic resonance imaging (MRI) and NIR-II cancer therapy agents. Combining these characteristics, we propose an MRI-guided approach to precision cancer therapy that offers a pathway for the rapid advancement of nanomedicine.https://doi.org/10.1038/s41467-025-60951-7 |
| spellingShingle | Tesen Zhang Quansheng Cheng Hongwei Cheng Qingcheng Wang Bingzhe Wang Bohan Zhang Handong Sun Chuxia Deng Zikang Tang Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy Nature Communications |
| title | Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy |
| title_full | Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy |
| title_fullStr | Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy |
| title_full_unstemmed | Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy |
| title_short | Manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and NIR-II photo-thermoelectric therapy |
| title_sort | manipulation of magnetic edge states in carbon quantum dots for magnetic resonance imaging and nir ii photo thermoelectric therapy |
| url | https://doi.org/10.1038/s41467-025-60951-7 |
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