AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing

AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing

Abstract Current methods for producing cardiomyocytes from human induced pluripotent stem cells (hiPSCs) using 2D monolayer differentiation are often hampered by batch-to-batch variability and inefficient purification processes. Here, we introduce CM-AI, a novel artificial intelligence-guided laser...

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Main Authors: Prakaimuk Saraithong, Peyton Krajcarski, Yukako Kusaka, Moe Yamada, Junichi Matsumoto, Hailey Cunningham, Sama Salih, Darby Jones, Devika Baddhan, Christian Hausner, Justus Anumonwo, Anthony Rosenzweig, Mary M. Navarro, Luis Villa Diaz, Joseph Criscione, Deok-Ho Kim, Todd J. Herron
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08162-0
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