Real‐Time VCC Monitoring and Forecasting in HEK‐Cell‐Based rAAV Vector Production Using Capacitance Spectroscopy

ABSTRACT Recombinant adeno‐associated virus (rAAV) vector production is a complex process in which the robust cultivation of human embryonic kidney cells (HEK293) plays a critical role in generating high‐quality viral vectors. Tracking the viable cell concentration (VCC) during upstream production i...

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Bibliographic Details
Main Authors: Rafael Machleid, Suneetha Nunna, Ajith George, Jonas Austerjost, Magda Tomala, Izabella Surowiec
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:Engineering in Life Sciences
Online Access:https://doi.org/10.1002/elsc.70004
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