Real‐Time VCC Monitoring and Forecasting in HEK‐Cell‐Based rAAV Vector Production Using Capacitance Spectroscopy

Real‐Time VCC Monitoring and Forecasting in HEK‐Cell‐Based rAAV Vector Production Using Capacitance Spectroscopy

ABSTRACT Recombinant adeno‐associated virus (rAAV) vector production is a complex process in which the robust cultivation of human embryonic kidney cells (HEK293) plays a critical role in generating high‐quality viral vectors. Tracking the viable cell concentration (VCC) during upstream production i...

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Bibliographic Details
Main Authors: Rafael Machleid, Suneetha Nunna, Ajith George, Jonas Austerjost, Magda Tomala, Izabella Surowiec
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:Engineering in Life Sciences
Online Access:https://doi.org/10.1002/elsc.70004
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