Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review

Bioprinting and bioinks are two of the game changers in bone tissue engineering. This review presents different bioprinting technologies including extrusion-based, inkjet-based, laser-assisted, light-based, and hybrid technologies with their own strengths and weaknesses. This review will aid researc...

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Main Authors: Elena Alina Chiticaru, Mariana Ioniță
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004022
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author Elena Alina Chiticaru
Mariana Ioniță
author_facet Elena Alina Chiticaru
Mariana Ioniță
author_sort Elena Alina Chiticaru
collection DOAJ
description Bioprinting and bioinks are two of the game changers in bone tissue engineering. This review presents different bioprinting technologies including extrusion-based, inkjet-based, laser-assisted, light-based, and hybrid technologies with their own strengths and weaknesses. This review will aid researchers in the selection and assessment of the bioink; the discussion ranges from commercially available bioinks to custom lab-made formulations mainly based on natural polymers, such as agarose, alginate, gelatin, collagen, and chitosan, designed for bone tissue engineering. The review is centered on technological advancements and increasing clinical demand within the rapidly growing bioprinting market. From this point of view, 4D, 5D, and 6D printing technologies promise a future where unprecedented levels of innovation will be involved in fabrication processes leading to more dynamic multifunctionalities of bioprinted constructs. Further advances in bioprinting technology, such as hybrid bioprinting methods are covered, with the promise to meet personalized medicine goals while advancing patient outcomes for bone tissues engineering applications.
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spelling doaj-art-5ef6cfdd27f044b3ac2ee244dfd7a91e2025-08-20T02:37:43ZengElsevierMaterials Today Bio2590-00642024-12-012910134110.1016/j.mtbio.2024.101341Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive reviewElena Alina Chiticaru0Mariana Ioniță1Faculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, Gh Polizu 1-7, 011061, Bucharest, RomaniaFaculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, Gh Polizu 1-7, 011061, Bucharest, Romania; Advanced Polymer Materials Group, National University of Science and Technology Politehnica Bucharest, Gh Polizu 1-7, 011061, Bucharest, Romania; Corresponding author. Faculty of Medical Engineering, National University of Science and Technology Politehnica Bucharest, Gh Polizu 1-7, 011061, Bucharest, Romania.Bioprinting and bioinks are two of the game changers in bone tissue engineering. This review presents different bioprinting technologies including extrusion-based, inkjet-based, laser-assisted, light-based, and hybrid technologies with their own strengths and weaknesses. This review will aid researchers in the selection and assessment of the bioink; the discussion ranges from commercially available bioinks to custom lab-made formulations mainly based on natural polymers, such as agarose, alginate, gelatin, collagen, and chitosan, designed for bone tissue engineering. The review is centered on technological advancements and increasing clinical demand within the rapidly growing bioprinting market. From this point of view, 4D, 5D, and 6D printing technologies promise a future where unprecedented levels of innovation will be involved in fabrication processes leading to more dynamic multifunctionalities of bioprinted constructs. Further advances in bioprinting technology, such as hybrid bioprinting methods are covered, with the promise to meet personalized medicine goals while advancing patient outcomes for bone tissues engineering applications.http://www.sciencedirect.com/science/article/pii/S2590006424004022Bone tissue engineeringBioprintingCommercial bioinkPrintable formulation
spellingShingle Elena Alina Chiticaru
Mariana Ioniță
Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
Materials Today Bio
Bone tissue engineering
Bioprinting
Commercial bioink
Printable formulation
title Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
title_full Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
title_fullStr Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
title_full_unstemmed Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
title_short Commercially available bioinks and state-of-the-art lab-made formulations for bone tissue engineering: A comprehensive review
title_sort commercially available bioinks and state of the art lab made formulations for bone tissue engineering a comprehensive review
topic Bone tissue engineering
Bioprinting
Commercial bioink
Printable formulation
url http://www.sciencedirect.com/science/article/pii/S2590006424004022
work_keys_str_mv AT elenaalinachiticaru commerciallyavailablebioinksandstateoftheartlabmadeformulationsforbonetissueengineeringacomprehensivereview
AT marianaionita commerciallyavailablebioinksandstateoftheartlabmadeformulationsforbonetissueengineeringacomprehensivereview