Exogenous LEA proteins expression enhances cold tolerance in mammalian cells by reducing oxidative stress

Exogenous LEA proteins expression enhances cold tolerance in mammalian cells by reducing oxidative stress

Abstract Understanding the molecular mechanisms that confer cold resistance in mammalian cells might be relevant for advancing medical applications. This study aimed to exploit the protective function of Late Embryogenesis Abundant (LEA) proteins, known to provide resistance to low temperatures in e...

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Bibliographic Details
Main Authors: Martina Lo Sterzo, Domenico Iuso, Luca Palazzese, Margherita Moncada, Francesca Boffa, Aurora Scudieri, Luisa Gioia, Marta Czernik, Pasqualino Loi
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Late Embryogenesis Abundant proteins
Cells
Cryoprotection
Antioxidants
Online Access:https://doi.org/10.1038/s41598-025-86499-6
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