Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector

Oviductus Ranae (OR) is one of the “treasures of Changbai Mountain” in China. It is used clinically for the treatment of infirmity after illness, fatigued spirit, cough, hemoptysis, and so forth. In this study, a simple and sensitive high-performance liquid chromatography-diode array detector (HPLC-...

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Main Authors: Yang Xu, Xianwen Yue, Jihong Chi, Huailei Yang, Ying Wang, Yongsheng Wang, Peng Yu, Huiwei Bao
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2024/3524367
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author Yang Xu
Xianwen Yue
Jihong Chi
Huailei Yang
Ying Wang
Yongsheng Wang
Peng Yu
Huiwei Bao
author_facet Yang Xu
Xianwen Yue
Jihong Chi
Huailei Yang
Ying Wang
Yongsheng Wang
Peng Yu
Huiwei Bao
author_sort Yang Xu
collection DOAJ
description Oviductus Ranae (OR) is one of the “treasures of Changbai Mountain” in China. It is used clinically for the treatment of infirmity after illness, fatigued spirit, cough, hemoptysis, and so forth. In this study, a simple and sensitive high-performance liquid chromatography-diode array detector (HPLC-DAD) method was developed for the simultaneous determination of five main effective components (1-methyl hydantoin, estradiol, cholesterol, 7-keto-cholesterol, and 4-cholesten-3-one) in OR and its different processed products. The results indicated that these five components showed good linear relationships within their own concentration ranges along with coefficients of determination ≥0.9996. Average recoveries ranged from 97.67% to 100.06%, with RSDs of 1.45%–1.99%. The proposed method was found to be simple, accurate, and stable, which provided an effective analytical method for quality control and evaluation of OR and its different processed products.
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id doaj-art-5eee9d10d5fb4cf5ab3b637ca0a8da83
institution Kabale University
issn 2090-9071
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-5eee9d10d5fb4cf5ab3b637ca0a8da832025-08-20T03:34:22ZengWileyJournal of Chemistry2090-90712024-01-01202410.1155/2024/3524367Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array DetectorYang Xu0Xianwen Yue1Jihong Chi2Huailei Yang3Ying Wang4Yongsheng Wang5Peng Yu6Huiwei Bao7College of PharmacyCollege of PharmacyCollege of PharmacyDepartment of PharmacyPlant Chemistry LaboratoryCollege of PharmacyCollege of PharmacyCollege of PharmacyOviductus Ranae (OR) is one of the “treasures of Changbai Mountain” in China. It is used clinically for the treatment of infirmity after illness, fatigued spirit, cough, hemoptysis, and so forth. In this study, a simple and sensitive high-performance liquid chromatography-diode array detector (HPLC-DAD) method was developed for the simultaneous determination of five main effective components (1-methyl hydantoin, estradiol, cholesterol, 7-keto-cholesterol, and 4-cholesten-3-one) in OR and its different processed products. The results indicated that these five components showed good linear relationships within their own concentration ranges along with coefficients of determination ≥0.9996. Average recoveries ranged from 97.67% to 100.06%, with RSDs of 1.45%–1.99%. The proposed method was found to be simple, accurate, and stable, which provided an effective analytical method for quality control and evaluation of OR and its different processed products.http://dx.doi.org/10.1155/2024/3524367
spellingShingle Yang Xu
Xianwen Yue
Jihong Chi
Huailei Yang
Ying Wang
Yongsheng Wang
Peng Yu
Huiwei Bao
Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
Journal of Chemistry
title Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
title_full Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
title_fullStr Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
title_full_unstemmed Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
title_short Analysis of the Influence of Different Processing Methods on the Main Effective Components in Oviductus Ranae by High-Performance Liquid Chromatography with Diode Array Detector
title_sort analysis of the influence of different processing methods on the main effective components in oviductus ranae by high performance liquid chromatography with diode array detector
url http://dx.doi.org/10.1155/2024/3524367
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