Combined Spatial and Dosimetric Recurrence Pattern Analysis in Head and Neck Squamous Cell Carcinoma Following Postoperative (Chemo)radiotherapy

Combined Spatial and Dosimetric Recurrence Pattern Analysis in Head and Neck Squamous Cell Carcinoma Following Postoperative (Chemo)radiotherapy

Abstract Background Advancements in nodal staging for head and neck squamous cell carcinoma (HNSCC) have prompted radiotherapy de-escalation trials to reduce irradiation of electively treated neck regions, with the goal of improving treatment tolerability. While volumetric de-escalation has shown pr...

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Main Authors: Philipp Schröter, Hoi Hin Lau, Florian Stritzke, Henrik Franke, Katharina Weusthof, Sebastian Regnery, Lukas Bauer, Maximilian Deng, Katharina Dvornikovich, Anna Hofmann, Lars Wessel, Karl Semmelmayer, Julius Moratin, Oliver Ristow, Jürgen Hoffmann, Peter Plinkert, Gerhard Dyckhoff, Jürgen Debus, Thomas Held
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Radiation Oncology
Subjects:
Recurrence patterns
Postoperative radiation therapy
Oral cavity cancer
Head and neck cancer
Local control
Dosimetric analysis
Online Access:https://doi.org/10.1186/s13014-025-02641-8
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