Cancer Immunotherapy and Abnormal Lipid Metabolism
Lipid metabolism relates to tumor proliferation, progression, and immune escape. With the rapid development of immunotherapy, the relationship between immunotherapy and lipid metabolism has been constantly explored. On the one hand, immunotherapy can cause dyslipidemia and accelerate the progression...
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| Format: | Article |
| Language: | zho |
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Magazine House of Cancer Research on Prevention and Treatment
2025-05-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1253 |
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| _version_ | 1850123680005226496 |
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| author | Wenxin JIANG Peng LIU |
| author_facet | Wenxin JIANG Peng LIU |
| author_sort | Wenxin JIANG |
| collection | DOAJ |
| description | Lipid metabolism relates to tumor proliferation, progression, and immune escape. With the rapid development of immunotherapy, the relationship between immunotherapy and lipid metabolism has been constantly explored. On the one hand, immunotherapy can cause dyslipidemia and accelerate the progression of atherosclerosis, which has been neglected by clinicians. On the other hand, lipid metabolism can affect antitumor immunity at multiple levels and potentially influence the efficacy of immunotherapy. Lipid metabolism-regulating drugs also have the potential to synergize with immunotherapy. This review summarizes relevant research evidence to inspire further exploration. |
| format | Article |
| id | doaj-art-5ee38b8ff1b84b02b6c07da1f696b345 |
| institution | OA Journals |
| issn | 1000-8578 |
| language | zho |
| publishDate | 2025-05-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj-art-5ee38b8ff1b84b02b6c07da1f696b3452025-08-20T02:34:32ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782025-05-0152535536010.3971/j.issn.1000-8578.2025.24.125320241253Cancer Immunotherapy and Abnormal Lipid MetabolismWenxin JIANG0Peng LIU1Medical Oncology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, ChinaMedical Oncology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, ChinaLipid metabolism relates to tumor proliferation, progression, and immune escape. With the rapid development of immunotherapy, the relationship between immunotherapy and lipid metabolism has been constantly explored. On the one hand, immunotherapy can cause dyslipidemia and accelerate the progression of atherosclerosis, which has been neglected by clinicians. On the other hand, lipid metabolism can affect antitumor immunity at multiple levels and potentially influence the efficacy of immunotherapy. Lipid metabolism-regulating drugs also have the potential to synergize with immunotherapy. This review summarizes relevant research evidence to inspire further exploration.http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1253immunotherapyimmune checkpoint inhibitorsdyslipidemia |
| spellingShingle | Wenxin JIANG Peng LIU Cancer Immunotherapy and Abnormal Lipid Metabolism Zhongliu Fangzhi Yanjiu immunotherapy immune checkpoint inhibitors dyslipidemia |
| title | Cancer Immunotherapy and Abnormal Lipid Metabolism |
| title_full | Cancer Immunotherapy and Abnormal Lipid Metabolism |
| title_fullStr | Cancer Immunotherapy and Abnormal Lipid Metabolism |
| title_full_unstemmed | Cancer Immunotherapy and Abnormal Lipid Metabolism |
| title_short | Cancer Immunotherapy and Abnormal Lipid Metabolism |
| title_sort | cancer immunotherapy and abnormal lipid metabolism |
| topic | immunotherapy immune checkpoint inhibitors dyslipidemia |
| url | http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1253 |
| work_keys_str_mv | AT wenxinjiang cancerimmunotherapyandabnormallipidmetabolism AT pengliu cancerimmunotherapyandabnormallipidmetabolism |