Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.

<h4>Aim</h4>To emphasize the importance of promptly assessment of punctate outer retinal toxoplasmosis (PORT), and to present a case series in a third-level reference center in Mexico City.<h4>Methods</h4>Retrospective, observational case series of eight eyes of eight patient...

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Main Authors: Rebeca Paquentín-Jiménez, Ronald Rivera-Sempértegui, Luz Elena Concha-Del-Río
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013013
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author Rebeca Paquentín-Jiménez
Ronald Rivera-Sempértegui
Luz Elena Concha-Del-Río
author_facet Rebeca Paquentín-Jiménez
Ronald Rivera-Sempértegui
Luz Elena Concha-Del-Río
author_sort Rebeca Paquentín-Jiménez
collection DOAJ
description <h4>Aim</h4>To emphasize the importance of promptly assessment of punctate outer retinal toxoplasmosis (PORT), and to present a case series in a third-level reference center in Mexico City.<h4>Methods</h4>Retrospective, observational case series of eight eyes of eight patients who presented PORT between January 2020 to February 2023. Diagnosis was made by uveitis specialists based on clinical findings, serology, and multimodal imaging. Descriptive statistics were used to exhibit absolute and relative frequencies.<h4>Results</h4>Patient ages ranged from 19 years to 67 years old. Each patient presented creamy yellowish-white, punctate outer retinal lesions. All patients had SD-OCT showed outer retinal alterations and in autofluorescence presented hyperautofluorescent lesions. 85% of the patients improved their BCVA after treatment, but three (42.8%) were legally blind.<h4>Conclusions</h4>PORT is an atypical presentation of ocular toxoplasmosis. Lesions usually lead to retinochoroidal scarring which can significantly diminish a patient's BCVA irreversibly. Recognition of PORT lesions is important since timely and efficacious therapy leads to better visual prognosis and diminish the risk of legal blindness.
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publishDate 2025-04-01
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spelling doaj-art-5edfcc80e57745168d7da906dc40a9872025-08-20T03:05:46ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352025-04-01194e001301310.1371/journal.pntd.0013013Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.Rebeca Paquentín-JiménezRonald Rivera-SempérteguiLuz Elena Concha-Del-Río<h4>Aim</h4>To emphasize the importance of promptly assessment of punctate outer retinal toxoplasmosis (PORT), and to present a case series in a third-level reference center in Mexico City.<h4>Methods</h4>Retrospective, observational case series of eight eyes of eight patients who presented PORT between January 2020 to February 2023. Diagnosis was made by uveitis specialists based on clinical findings, serology, and multimodal imaging. Descriptive statistics were used to exhibit absolute and relative frequencies.<h4>Results</h4>Patient ages ranged from 19 years to 67 years old. Each patient presented creamy yellowish-white, punctate outer retinal lesions. All patients had SD-OCT showed outer retinal alterations and in autofluorescence presented hyperautofluorescent lesions. 85% of the patients improved their BCVA after treatment, but three (42.8%) were legally blind.<h4>Conclusions</h4>PORT is an atypical presentation of ocular toxoplasmosis. Lesions usually lead to retinochoroidal scarring which can significantly diminish a patient's BCVA irreversibly. Recognition of PORT lesions is important since timely and efficacious therapy leads to better visual prognosis and diminish the risk of legal blindness.https://doi.org/10.1371/journal.pntd.0013013
spellingShingle Rebeca Paquentín-Jiménez
Ronald Rivera-Sempértegui
Luz Elena Concha-Del-Río
Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
PLoS Neglected Tropical Diseases
title Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
title_full Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
title_fullStr Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
title_full_unstemmed Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
title_short Small but threatening: Punctate Outer Retinal Toxoplasmosis (PORT), a case series report.
title_sort small but threatening punctate outer retinal toxoplasmosis port a case series report
url https://doi.org/10.1371/journal.pntd.0013013
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