Simulation and Quantitative Analysis of Spatial Centromere Distribution Patterns

A prominent feature of eukaryotic chromosomes are centromeres, which are specialized regions of repetitive DNA required for faithful chromosome segregation during cell division. In interphase cells, centromeres are non-randomly positioned in the three-dimensional space of the nucleus in a cell type-...

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Bibliographic Details
Main Authors: Adib Keikhosravi, Krishnendu Guin, Gianluca Pegoraro, Tom Misteli
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/7/491
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