Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their b...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2015/832057 |
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| _version_ | 1832559974611419136 |
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| author | João Henrique Campos Rodrigo Pedro Soares Kleber Ribeiro André Cronemberger Andrade Wagner Luiz Batista Ana Claudia Torrecilhas |
| author_facet | João Henrique Campos Rodrigo Pedro Soares Kleber Ribeiro André Cronemberger Andrade Wagner Luiz Batista Ana Claudia Torrecilhas |
| author_sort | João Henrique Campos |
| collection | DOAJ |
| description | Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases. |
| format | Article |
| id | doaj-art-5ed4a2979e5748e6a124184efd37e2b3 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-5ed4a2979e5748e6a124184efd37e2b32025-02-03T01:28:41ZengWileyJournal of Immunology Research2314-88612314-71562015-01-01201510.1155/2015/832057832057Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious DiseasesJoão Henrique Campos0Rodrigo Pedro Soares1Kleber Ribeiro2André Cronemberger Andrade3Wagner Luiz Batista4Ana Claudia Torrecilhas5Laboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, 09913-030 São Paulo, SP, BrazilLaboratório de Parasitologia Celular e Molecular, Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, 30190-002 Belo Horizonte, MG, BrazilLaboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, 09913-030 São Paulo, SP, BrazilLaboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, 09913-030 São Paulo, SP, BrazilLaboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, 09913-030 São Paulo, SP, BrazilLaboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Biológicas, Universidade Federal de São Paulo (UNIFESP), Campus Diadema, 09913-030 São Paulo, SP, BrazilAlmost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases.http://dx.doi.org/10.1155/2015/832057 |
| spellingShingle | João Henrique Campos Rodrigo Pedro Soares Kleber Ribeiro André Cronemberger Andrade Wagner Luiz Batista Ana Claudia Torrecilhas Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases Journal of Immunology Research |
| title | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
| title_full | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
| title_fullStr | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
| title_full_unstemmed | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
| title_short | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
| title_sort | extracellular vesicles role in inflammatory responses and potential uses in vaccination in cancer and infectious diseases |
| url | http://dx.doi.org/10.1155/2015/832057 |
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