EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO
Abstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/372 |
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| Summary: | Abstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone does not significantly affect phagocytic function of monocytes at concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy, however, leads to increased formation of extracellular traps and increase of oxygen-dependent bactericidal effects. |
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| ISSN: | 1563-0625 2313-741X |