Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects

Bioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne patho...

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Main Authors: Anowar Khasru Parvez, Fatema Tuz Jubyda, Mohammed Ayaz, Amily Sarker, Nabila Haque, Md. Shahriar Khan, Taslin Jahan Mou, Md. Atikur Rahman, Md. Amdadul Huq
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2024/9978033
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author Anowar Khasru Parvez
Fatema Tuz Jubyda
Mohammed Ayaz
Amily Sarker
Nabila Haque
Md. Shahriar Khan
Taslin Jahan Mou
Md. Atikur Rahman
Md. Amdadul Huq
author_facet Anowar Khasru Parvez
Fatema Tuz Jubyda
Mohammed Ayaz
Amily Sarker
Nabila Haque
Md. Shahriar Khan
Taslin Jahan Mou
Md. Atikur Rahman
Md. Amdadul Huq
author_sort Anowar Khasru Parvez
collection DOAJ
description Bioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne pathogens. BAPs have several other useful properties including antitumor, antihypertensive, antioxidant, antiobesity, and antidiabetic activities. Nowadays, scientists have attempted to recombinantly synthesize bioactive peptides to study their characteristics and potential uses, since BAPs are not found in large quantities in nature. Many pathogenic microorganisms including foodborne pathogens are becoming resistant to various antibiotics. To combat these pathogens, scientists are working to find novel, innovative, and safe antimicrobial agents. Plant- and microbe-based BAPs have demonstrated noteworthy antimicrobial activity against a wide range of pathogenic microorganisms, including foodborne pathogens. BAPs can kill pathogenic microorganisms by disrupting membrane integrity, inhibiting DNA and RNA synthesis, preventing protein synthesis, blocking protein activity, or interacting with certain intracellular targets. In addition, the positive effect of BAP consumption extends to gut microbiota modulation and affects the equilibrium of reactive oxygen species in the gut. This article discusses recombinant BAPs, BAPs generated from plants and microbes, and their antimicrobial applications and modes of action for controlling foodborne pathogens.
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spelling doaj-art-5eb6becfa3d5455496aa9b4028ef14602025-08-20T02:05:10ZengWileyInternational Journal of Microbiology1687-91982024-01-01202410.1155/2024/9978033Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future ProspectsAnowar Khasru Parvez0Fatema Tuz Jubyda1Mohammed Ayaz2Amily Sarker3Nabila Haque4Md. Shahriar Khan5Taslin Jahan Mou6Md. Atikur Rahman7Md. Amdadul Huq8Department of MicrobiologyDepartment of MicrobiologyDepartment of MicrobiologyDepartment of MicrobiologyDepartment of MicrobiologyDepartment of MicrobiologyDepartment of MicrobiologyInstitute of BiodiversityDepartment of Food and NutritionBioactive peptides (BAPs) obtained from plants and microbes have been thoroughly explored and studied due to their prophylactic properties. The use of BAPs seems to be a promising substitute for several currently available antibiotics because of their antimicrobial properties against foodborne pathogens. BAPs have several other useful properties including antitumor, antihypertensive, antioxidant, antiobesity, and antidiabetic activities. Nowadays, scientists have attempted to recombinantly synthesize bioactive peptides to study their characteristics and potential uses, since BAPs are not found in large quantities in nature. Many pathogenic microorganisms including foodborne pathogens are becoming resistant to various antibiotics. To combat these pathogens, scientists are working to find novel, innovative, and safe antimicrobial agents. Plant- and microbe-based BAPs have demonstrated noteworthy antimicrobial activity against a wide range of pathogenic microorganisms, including foodborne pathogens. BAPs can kill pathogenic microorganisms by disrupting membrane integrity, inhibiting DNA and RNA synthesis, preventing protein synthesis, blocking protein activity, or interacting with certain intracellular targets. In addition, the positive effect of BAP consumption extends to gut microbiota modulation and affects the equilibrium of reactive oxygen species in the gut. This article discusses recombinant BAPs, BAPs generated from plants and microbes, and their antimicrobial applications and modes of action for controlling foodborne pathogens.http://dx.doi.org/10.1155/2024/9978033
spellingShingle Anowar Khasru Parvez
Fatema Tuz Jubyda
Mohammed Ayaz
Amily Sarker
Nabila Haque
Md. Shahriar Khan
Taslin Jahan Mou
Md. Atikur Rahman
Md. Amdadul Huq
Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
International Journal of Microbiology
title Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
title_full Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
title_fullStr Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
title_full_unstemmed Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
title_short Microbial- and Plant-Derived Bioactive Peptides and Their Applications against Foodborne Pathogens: Current Status and Future Prospects
title_sort microbial and plant derived bioactive peptides and their applications against foodborne pathogens current status and future prospects
url http://dx.doi.org/10.1155/2024/9978033
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