The Epidemiology of Immune Thrombocytopenia

Three cases of immune thrombocytopenia (ITP) associated with human immunodeficiency virus (HIV) infection prompted a review of community-acquired thrombocytopenia in Nova Scotia from January 1980 to December 1987. Two hundred and seven patients meeting the case definition of ITP were identified. The...

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Main Authors: Walter F Schlech, Christine Nesdoly, Nancy Meagher, Janet Turner, Donalda Dickey
Format: Article
Language:English
Published: Wiley 1992-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1992/164259
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author Walter F Schlech
Christine Nesdoly
Nancy Meagher
Janet Turner
Donalda Dickey
author_facet Walter F Schlech
Christine Nesdoly
Nancy Meagher
Janet Turner
Donalda Dickey
author_sort Walter F Schlech
collection DOAJ
description Three cases of immune thrombocytopenia (ITP) associated with human immunodeficiency virus (HIV) infection prompted a review of community-acquired thrombocytopenia in Nova Scotia from January 1980 to December 1987. Two hundred and seven patients meeting the case definition of ITP were identified. The incidence of ITP rose from 2.0×105 in 1980 to 3.3×105 in 1987. More cases of ITP in the sexually active population occurred between 1984 and 1987 than in the previous four years (P=0.034). All three cases of known HIV associated ITP were captured in the retrospective surveillance system. The study concluded that increases in community-acquired ITP in a sexually active population may be a surrogate marker of the HIV epidemic, even in geographic areas with a low seroprevalence for HIV. Serological tests for HIV infection should be a routine part of the diagnostic investigation of ITP in all sexually active patients or those with other potential risk factors for HIV infection.
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spelling doaj-art-5eb5b2e4180b4fecaf633f3085410fcf2025-08-20T03:34:33ZengWileyCanadian Journal of Infectious Diseases1180-23321992-01-013631131410.1155/1992/164259The Epidemiology of Immune ThrombocytopeniaWalter F Schlech0Christine Nesdoly1Nancy Meagher2Janet Turner3Donalda Dickey4Dalhousie University, Faculty of Medicine, Halifax, Nova Scotia, CanadaDalhousie University, Faculty of Medicine, Halifax, Nova Scotia, CanadaDalhousie University, Faculty of Medicine, Halifax, Nova Scotia, CanadaDalhousie University, Faculty of Medicine, Halifax, Nova Scotia, CanadaDalhousie University, Faculty of Medicine, Halifax, Nova Scotia, CanadaThree cases of immune thrombocytopenia (ITP) associated with human immunodeficiency virus (HIV) infection prompted a review of community-acquired thrombocytopenia in Nova Scotia from January 1980 to December 1987. Two hundred and seven patients meeting the case definition of ITP were identified. The incidence of ITP rose from 2.0×105 in 1980 to 3.3×105 in 1987. More cases of ITP in the sexually active population occurred between 1984 and 1987 than in the previous four years (P=0.034). All three cases of known HIV associated ITP were captured in the retrospective surveillance system. The study concluded that increases in community-acquired ITP in a sexually active population may be a surrogate marker of the HIV epidemic, even in geographic areas with a low seroprevalence for HIV. Serological tests for HIV infection should be a routine part of the diagnostic investigation of ITP in all sexually active patients or those with other potential risk factors for HIV infection.http://dx.doi.org/10.1155/1992/164259
spellingShingle Walter F Schlech
Christine Nesdoly
Nancy Meagher
Janet Turner
Donalda Dickey
The Epidemiology of Immune Thrombocytopenia
Canadian Journal of Infectious Diseases
title The Epidemiology of Immune Thrombocytopenia
title_full The Epidemiology of Immune Thrombocytopenia
title_fullStr The Epidemiology of Immune Thrombocytopenia
title_full_unstemmed The Epidemiology of Immune Thrombocytopenia
title_short The Epidemiology of Immune Thrombocytopenia
title_sort epidemiology of immune thrombocytopenia
url http://dx.doi.org/10.1155/1992/164259
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