Modern ideas about pharmacotherapy of pelvic congestion syndrome in women

Pelvic congestion syndrome (PCS) is not a rare and poorly studied disease. However, the current state of PCS pharmacotherapy is characterized not only by insufficient study of this issue, but also by the presence of conflicting views. The results of key publications prove that the main trend in PCS...

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Main Authors: R. V. Akhmetzianov, R. A. Bredikhin
Format: Article
Language:Russian
Published: Remedium Group LTD 2024-11-01
Series:Амбулаторная хирургия
Subjects:
Online Access:https://www.a-surgeon.ru/jour/article/view/473
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author R. V. Akhmetzianov
R. A. Bredikhin
author_facet R. V. Akhmetzianov
R. A. Bredikhin
author_sort R. V. Akhmetzianov
collection DOAJ
description Pelvic congestion syndrome (PCS) is not a rare and poorly studied disease. However, the current state of PCS pharmacotherapy is characterized not only by insufficient study of this issue, but also by the presence of conflicting views. The results of key publications prove that the main trend in PCS treatment is associated with invasive methods. At the same time, pharmacotherapy is a successful solution leading to the relief of the main symptoms in most patients with PCS. The current review is based on the analysis of data from known scientific literature and clinical guidelines. It covers various aspects of conservative treatment of patients with PCS and focuses on pharmacotherapy. This publication aims to summarize the known data related to drug correction of PCS, based on evidence-based medicine. The review presents information related to the history of the selection of pharmacotherapy, including combinations of drugs of various groups with the appointment of analgesics, hormonal, psychotropic, venoactive drugs and selective vasoconstrictors. An objective analysis of each of the indicated pharmacological groups of drugs is presented with an assessment of subsequent prospects, including not only known therapeutic agents, but also those not previously used in the therapy of PCS. The drug of choice in the arsenal of the attending physician are vasoactive drugs based on diosmin with the largest evidence base in MPFF. In the presence of severe pain syndrome, short-term administration of analgesics is advisable. The presence of anxiety-depressive disorders, as well as severe CPP, can serve as an indication for taking psychotropic drugs. Further research is needed to expand the potential of pharmacotherapy for patients with PCS.
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spelling doaj-art-5ea942cbf22c4f5ca35c3513dec8c06d2025-08-20T03:05:29ZrusRemedium Group LTDАмбулаторная хирургия2712-87412782-25912024-11-012129410310.21518/akh2024-039367Modern ideas about pharmacotherapy of pelvic congestion syndrome in womenR. V. Akhmetzianov0R. A. Bredikhin1Kazan State Medical University; Interregional Clinical Diagnostic CenterKazan State Medical University; Interregional Clinical Diagnostic CenterPelvic congestion syndrome (PCS) is not a rare and poorly studied disease. However, the current state of PCS pharmacotherapy is characterized not only by insufficient study of this issue, but also by the presence of conflicting views. The results of key publications prove that the main trend in PCS treatment is associated with invasive methods. At the same time, pharmacotherapy is a successful solution leading to the relief of the main symptoms in most patients with PCS. The current review is based on the analysis of data from known scientific literature and clinical guidelines. It covers various aspects of conservative treatment of patients with PCS and focuses on pharmacotherapy. This publication aims to summarize the known data related to drug correction of PCS, based on evidence-based medicine. The review presents information related to the history of the selection of pharmacotherapy, including combinations of drugs of various groups with the appointment of analgesics, hormonal, psychotropic, venoactive drugs and selective vasoconstrictors. An objective analysis of each of the indicated pharmacological groups of drugs is presented with an assessment of subsequent prospects, including not only known therapeutic agents, but also those not previously used in the therapy of PCS. The drug of choice in the arsenal of the attending physician are vasoactive drugs based on diosmin with the largest evidence base in MPFF. In the presence of severe pain syndrome, short-term administration of analgesics is advisable. The presence of anxiety-depressive disorders, as well as severe CPP, can serve as an indication for taking psychotropic drugs. Further research is needed to expand the potential of pharmacotherapy for patients with PCS.https://www.a-surgeon.ru/jour/article/view/473pelvic congestion syndromechronic pelvic painpelvic venous disorderspharmacotherapyconservative treatmentmpff
spellingShingle R. V. Akhmetzianov
R. A. Bredikhin
Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
Амбулаторная хирургия
pelvic congestion syndrome
chronic pelvic pain
pelvic venous disorders
pharmacotherapy
conservative treatment
mpff
title Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
title_full Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
title_fullStr Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
title_full_unstemmed Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
title_short Modern ideas about pharmacotherapy of pelvic congestion syndrome in women
title_sort modern ideas about pharmacotherapy of pelvic congestion syndrome in women
topic pelvic congestion syndrome
chronic pelvic pain
pelvic venous disorders
pharmacotherapy
conservative treatment
mpff
url https://www.a-surgeon.ru/jour/article/view/473
work_keys_str_mv AT rvakhmetzianov modernideasaboutpharmacotherapyofpelviccongestionsyndromeinwomen
AT rabredikhin modernideasaboutpharmacotherapyofpelviccongestionsyndromeinwomen