Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy

Abstract A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immu...

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Bibliographic Details
Main Authors: Quansheng Cheng, Qingcheng Wang, Songnan Qu
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-025-01757-6
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Summary:Abstract A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.
ISSN:2047-7538