Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel
Objective: To evaluate in vitro the erosive effect of long-term liquid oral pediatric medicines on human enamel teeth and the preventive action of fluoride in an erosive challenge. Material and Methods: Three commonly used medicines were selected for this study, and their endogenous pH was measured...
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| Format: | Article |
| Language: | English |
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Association of Support to Oral Health Research (APESB)
2025-02-01
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| Series: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
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| Online Access: | https://revista.uepb.edu.br/PBOCI/article/view/4287 |
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| author | Fábio Gomes dos Santos Ana Maria Barros Chaves Pereira Isabela Albuquerque Passos Farias Tibério Andrade dos Passos Andressa Feitosa Bezerra de Oliveira |
| author_facet | Fábio Gomes dos Santos Ana Maria Barros Chaves Pereira Isabela Albuquerque Passos Farias Tibério Andrade dos Passos Andressa Feitosa Bezerra de Oliveira |
| author_sort | Fábio Gomes dos Santos |
| collection | DOAJ |
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Objective: To evaluate in vitro the erosive effect of long-term liquid oral pediatric medicines on human enamel teeth and the preventive action of fluoride in an erosive challenge. Material and Methods: Three commonly used medicines were selected for this study, and their endogenous pH was measured in triplicate. Thirty permanent tooth enamel specimens were prepared and divided into six groups (n=5): E1 (Zetalerg), E2 (Betamethasone), E3 (Anemifer), E4 (Anemifer+Duraphat), E5 (Coke), and E6 (artificial saliva). Specimens were immersed in 5 ml of medicine solution for 5 min, 2x/ day for 12 days, and stored in artificial saliva at 37°C between immersions. Data analysis was performed according to the enamel surface morphology using SEM. Results: The medicines showed an acidic pH range from 2.09 to 4.14. All the specimens exposed to pediatric medicines presented some pit-like erosion pattern under SEM analysis, except for the E4 group. The degree of destruction was inversely proportional to pH formulation values. Morphology alterations could be ranked as follows: E3>E2>E1=E5. The E4 group, protected with varnish fluoride, did not present signs of surface erosion wear like E6. Conclusion: All the pediatric medicines used promoted some enamel tooth wear, with higher severity with low pH medicines. The presence of fluoride reduced the deleterious effect of pediatric medicines on human tooth enamel.
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| format | Article |
| id | doaj-art-5ea0870eaa7848fbaa3aab0d5483a9af |
| institution | Kabale University |
| issn | 1519-0501 1983-4632 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Association of Support to Oral Health Research (APESB) |
| record_format | Article |
| series | Pesquisa Brasileira em Odontopediatria e Clínica Integrada |
| spelling | doaj-art-5ea0870eaa7848fbaa3aab0d5483a9af2025-02-06T10:26:47ZengAssociation of Support to Oral Health Research (APESB)Pesquisa Brasileira em Odontopediatria e Clínica Integrada1519-05011983-46322025-02-0125Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth EnamelFábio Gomes dos SantosAna Maria Barros Chaves PereiraIsabela Albuquerque Passos FariasTibério Andrade dos PassosAndressa Feitosa Bezerra de Oliveira Objective: To evaluate in vitro the erosive effect of long-term liquid oral pediatric medicines on human enamel teeth and the preventive action of fluoride in an erosive challenge. Material and Methods: Three commonly used medicines were selected for this study, and their endogenous pH was measured in triplicate. Thirty permanent tooth enamel specimens were prepared and divided into six groups (n=5): E1 (Zetalerg), E2 (Betamethasone), E3 (Anemifer), E4 (Anemifer+Duraphat), E5 (Coke), and E6 (artificial saliva). Specimens were immersed in 5 ml of medicine solution for 5 min, 2x/ day for 12 days, and stored in artificial saliva at 37°C between immersions. Data analysis was performed according to the enamel surface morphology using SEM. Results: The medicines showed an acidic pH range from 2.09 to 4.14. All the specimens exposed to pediatric medicines presented some pit-like erosion pattern under SEM analysis, except for the E4 group. The degree of destruction was inversely proportional to pH formulation values. Morphology alterations could be ranked as follows: E3>E2>E1=E5. The E4 group, protected with varnish fluoride, did not present signs of surface erosion wear like E6. Conclusion: All the pediatric medicines used promoted some enamel tooth wear, with higher severity with low pH medicines. The presence of fluoride reduced the deleterious effect of pediatric medicines on human tooth enamel. https://revista.uepb.edu.br/PBOCI/article/view/4287Tooth ErosionMicroscopy, Electron, ScanningAntitussive AgentsDental Enamel |
| spellingShingle | Fábio Gomes dos Santos Ana Maria Barros Chaves Pereira Isabela Albuquerque Passos Farias Tibério Andrade dos Passos Andressa Feitosa Bezerra de Oliveira Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel Pesquisa Brasileira em Odontopediatria e Clínica Integrada Tooth Erosion Microscopy, Electron, Scanning Antitussive Agents Dental Enamel |
| title | Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel |
| title_full | Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel |
| title_fullStr | Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel |
| title_full_unstemmed | Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel |
| title_short | Erosive Effect of Long-Term Liquid Oral Pediatric Medicines on Permanent Tooth Enamel |
| title_sort | erosive effect of long term liquid oral pediatric medicines on permanent tooth enamel |
| topic | Tooth Erosion Microscopy, Electron, Scanning Antitussive Agents Dental Enamel |
| url | https://revista.uepb.edu.br/PBOCI/article/view/4287 |
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