Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis
ObjectiveAccording to clinical observation and recent studies, there is a significant association between night sleep duration and hyperuricemia. In this study, systematic review and network meta-analysis were performed to evaluate the risk of hyperuricemia associated with different nighttime sleep...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1436116/full |
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| author | Chun Luo FengQi Zhang Danqian Shen Jing Sun YuShan Zhang ZhiJun Xie XiaLi Yu |
| author_facet | Chun Luo FengQi Zhang Danqian Shen Jing Sun YuShan Zhang ZhiJun Xie XiaLi Yu |
| author_sort | Chun Luo |
| collection | DOAJ |
| description | ObjectiveAccording to clinical observation and recent studies, there is a significant association between night sleep duration and hyperuricemia. In this study, systematic review and network meta-analysis were performed to evaluate the risk of hyperuricemia associated with different nighttime sleep durations.MethodsSeven databases were searched from database inception to March 2020. Two reviewers independently performed study selection, quality appraisal, and data extraction. Conventional meta-analysis was conducted using either a fixed-effects or random-effects model according to statistical heterogeneity. A Bayesian network meta-analysis was conducted using the consistency model.ResultsSix studies with 416,684 patients and involving different nighttime sleep durations were included. The network meta-analysis showed that compared with normal nighttime sleep duration, the pooled risk ratio (RR) for short nighttime sleep duration was 1.26 (95% confidence interval [CI] 1.22–1.30, p < 0.00001). Compared with long nighttime sleep duration, pooled RR of HUA with normal nighttime sleep duration was 0.81 (95% CI 0.67–0.99, p = 0.03). Compared with long nighttime sleep duration, pooled RR of HUA with short nighttime sleep duration was 1.07 (95% CI 0.90–1.28, p = 0.43).ConclusionThe evidence in this network meta-analysis illustrates that both short and long sleep duration increased the risk of hyperuricemia, and short sleep duration was more harmful. Further high-quality studies are required to explore the Mechanism of the nighttime sleep duration influencing hyperuricemia.Systematic review registrationhttps://www.crd.york.ac.uk/, CRD42024519628. |
| format | Article |
| id | doaj-art-5ea075a9d49f4a719a0cc5a24edbf0d8 |
| institution | DOAJ |
| issn | 1662-453X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj-art-5ea075a9d49f4a719a0cc5a24edbf0d82025-08-20T02:56:07ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2025-05-011910.3389/fnins.2025.14361161436116Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysisChun Luo0FengQi Zhang1Danqian Shen2Jing Sun3YuShan Zhang4ZhiJun Xie5XiaLi Yu6The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, ChinaThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, ChinaDepartment of Orthopedics, Xinchang Hospital Affiliated to Wenzhou Medical University, Xinchang, ChinaSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, ChinaDepartment of Rheumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ChinaObjectiveAccording to clinical observation and recent studies, there is a significant association between night sleep duration and hyperuricemia. In this study, systematic review and network meta-analysis were performed to evaluate the risk of hyperuricemia associated with different nighttime sleep durations.MethodsSeven databases were searched from database inception to March 2020. Two reviewers independently performed study selection, quality appraisal, and data extraction. Conventional meta-analysis was conducted using either a fixed-effects or random-effects model according to statistical heterogeneity. A Bayesian network meta-analysis was conducted using the consistency model.ResultsSix studies with 416,684 patients and involving different nighttime sleep durations were included. The network meta-analysis showed that compared with normal nighttime sleep duration, the pooled risk ratio (RR) for short nighttime sleep duration was 1.26 (95% confidence interval [CI] 1.22–1.30, p < 0.00001). Compared with long nighttime sleep duration, pooled RR of HUA with normal nighttime sleep duration was 0.81 (95% CI 0.67–0.99, p = 0.03). Compared with long nighttime sleep duration, pooled RR of HUA with short nighttime sleep duration was 1.07 (95% CI 0.90–1.28, p = 0.43).ConclusionThe evidence in this network meta-analysis illustrates that both short and long sleep duration increased the risk of hyperuricemia, and short sleep duration was more harmful. Further high-quality studies are required to explore the Mechanism of the nighttime sleep duration influencing hyperuricemia.Systematic review registrationhttps://www.crd.york.ac.uk/, CRD42024519628.https://www.frontiersin.org/articles/10.3389/fnins.2025.1436116/fullnighttime sleep durationhyperuricemiasystematic reviewnetwork meta-analysisHUA |
| spellingShingle | Chun Luo FengQi Zhang Danqian Shen Jing Sun YuShan Zhang ZhiJun Xie XiaLi Yu Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis Frontiers in Neuroscience nighttime sleep duration hyperuricemia systematic review network meta-analysis HUA |
| title | Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis |
| title_full | Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis |
| title_fullStr | Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis |
| title_full_unstemmed | Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis |
| title_short | Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis |
| title_sort | nighttime sleep duration and the prevalence of hyperuricemia a systematic review and network meta analysis |
| topic | nighttime sleep duration hyperuricemia systematic review network meta-analysis HUA |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2025.1436116/full |
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