Semiautomated Multimodal Breast Image Registration

Consideration of information from multiple modalities has been shown to have increased diagnostic power in breast imaging. As a result, new techniques such as microwave imaging continue to be developed. Interpreting these novel image modalities is a challenge, requiring comparison to established tec...

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Main Authors: Charlotte Curtis, Richard Frayne, Elise Fear
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2012/890830
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author Charlotte Curtis
Richard Frayne
Elise Fear
author_facet Charlotte Curtis
Richard Frayne
Elise Fear
author_sort Charlotte Curtis
collection DOAJ
description Consideration of information from multiple modalities has been shown to have increased diagnostic power in breast imaging. As a result, new techniques such as microwave imaging continue to be developed. Interpreting these novel image modalities is a challenge, requiring comparison to established techniques such as the gold standard X-ray mammography. However, due to the highly deformable nature of breast tissues, comparison of 3D and 2D modalities is a challenge. To enable this comparison, a registration technique was developed to map features from 2D mammograms to locations in the 3D image space. This technique was developed and tested using magnetic resonance (MR) images as a reference 3D modality, as MR breast imaging is an established technique in clinical practice. The algorithm was validated using a numerical phantom then successfully tested on twenty-four image pairs. Dice's coefficient was used to measure the external goodness of fit, resulting in an excellent overall average of 0.94. Internal agreement was evaluated by examining internal features in consultation with a radiologist, and subjective assessment concludes that reasonable alignment was achieved.
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spelling doaj-art-5e9871ccf69649b29312375c19c57e7d2025-08-20T03:34:33ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962012-01-01201210.1155/2012/890830890830Semiautomated Multimodal Breast Image RegistrationCharlotte Curtis0Richard Frayne1Elise Fear2Department of Electrical and Computer Engineering, University of Calgary, Calgary, AB, T2N 1N4, CanadaDepartment of Radiology, University of Calgary, Calgary, AB, T2N 1N4, CanadaDepartment of Electrical and Computer Engineering, University of Calgary, Calgary, AB, T2N 1N4, CanadaConsideration of information from multiple modalities has been shown to have increased diagnostic power in breast imaging. As a result, new techniques such as microwave imaging continue to be developed. Interpreting these novel image modalities is a challenge, requiring comparison to established techniques such as the gold standard X-ray mammography. However, due to the highly deformable nature of breast tissues, comparison of 3D and 2D modalities is a challenge. To enable this comparison, a registration technique was developed to map features from 2D mammograms to locations in the 3D image space. This technique was developed and tested using magnetic resonance (MR) images as a reference 3D modality, as MR breast imaging is an established technique in clinical practice. The algorithm was validated using a numerical phantom then successfully tested on twenty-four image pairs. Dice's coefficient was used to measure the external goodness of fit, resulting in an excellent overall average of 0.94. Internal agreement was evaluated by examining internal features in consultation with a radiologist, and subjective assessment concludes that reasonable alignment was achieved.http://dx.doi.org/10.1155/2012/890830
spellingShingle Charlotte Curtis
Richard Frayne
Elise Fear
Semiautomated Multimodal Breast Image Registration
International Journal of Biomedical Imaging
title Semiautomated Multimodal Breast Image Registration
title_full Semiautomated Multimodal Breast Image Registration
title_fullStr Semiautomated Multimodal Breast Image Registration
title_full_unstemmed Semiautomated Multimodal Breast Image Registration
title_short Semiautomated Multimodal Breast Image Registration
title_sort semiautomated multimodal breast image registration
url http://dx.doi.org/10.1155/2012/890830
work_keys_str_mv AT charlottecurtis semiautomatedmultimodalbreastimageregistration
AT richardfrayne semiautomatedmultimodalbreastimageregistration
AT elisefear semiautomatedmultimodalbreastimageregistration