Sex shapes phenotype-linked metabolic signatures of stress exposure in the mouse hypothalamus and pituitary

Sex shapes phenotype-linked metabolic signatures of stress exposure in the mouse hypothalamus and pituitary

In chronic stress-induced anxiodepression, sex differences in the dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis are well-documented, yet the underlying molecular mechanisms remain largely unexplored. This study investigated sex-specific metabolic signatures associated with stress expo...

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Bibliographic Details
Main Authors: Lili Wang, Bingtao Jiang, Xunan Ji, Jiaxin Tu, Fengmei Lu, Chen Yang, Xianhui Zhong, Lu Wang, Xiao Cai, Faping Yi, Zongling He, Liang Xie, Jian Zhou
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Neurobiology of Disease
Subjects:
Chronic stress
Sex differences
Metabolic signatures
Hypothalamus
Pituitary
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125001147
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