Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review
This systematic review aims to demonstrate that coenzyme Q10 (CoQ10) supplementation may be an effective molecule in improving exercise performance and recovering muscle damage, improving antioxidant capacity, and suppressing inflammatory processes. The study covers the literature in PubMed, Google...
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| Format: | Article |
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Turkish Journal of Kinesiology
2024-03-01
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| Series: | Turkish Journal of Kinesiology |
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| Online Access: | https://dergipark.org.tr/en/download/article-file/3696472 |
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| author | Muhammet Enes Yasul Vedat Çınar Yavuz Yasul Büşra Yılmaz Ömer Şenel |
| author_facet | Muhammet Enes Yasul Vedat Çınar Yavuz Yasul Büşra Yılmaz Ömer Şenel |
| author_sort | Muhammet Enes Yasul |
| collection | DOAJ |
| description | This systematic review aims to demonstrate that coenzyme Q10 (CoQ10) supplementation may be an effective molecule in improving exercise performance and recovering muscle damage, improving antioxidant capacity, and suppressing inflammatory processes. The study covers the literature in PubMed, Google Scholar, Web of Science and Scopus databases from 2011 to 2023. The final review was conducted on June 6. In the literature analysis, eight keywords (exercise, oxidative stress, CoQ10, muscle damage, inflammation, skeletal muscle, heart muscle, and performance) were employed to investigate the publications. The full texts of 362 full texts of articles were included in this study. These were analyzed according to the PRISMA reporting criteria. In the analysis, one study was conducted with experimental animals, two studies were conducted with male and female participants, and 12 studies were conducted with only male participants. Participants in twelve studies were well-trained. However, two studies were conducted with a sedentary group. In addition, CoQ10 supplementation was present in all studies. CoQ10 supplementation was between 5-60 mg/kg in 4 studies and 100 mg/kg and above in the remaining 10 studies. Antioxidant capacities and inflammation markers were among the parameters of most interest. There were fewer studies on skeletal and cardiac muscle damage and performance markers. CoQ10 supplementation during intense exercise elevates plasma CoQ10 and antioxidant levels while reducing inflammation markers. Additionally, it enhances contractile function in sarcomeres and cardiomyocytes. Nevertheless, additional studies are necessary to comprehensively as certain CoQ10 impact on athletic performance. |
| format | Article |
| id | doaj-art-5e911ec687b34241b583d9a833ed2ed8 |
| institution | Kabale University |
| issn | 2459-0134 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Turkish Journal of Kinesiology |
| record_format | Article |
| series | Turkish Journal of Kinesiology |
| spelling | doaj-art-5e911ec687b34241b583d9a833ed2ed82025-01-24T12:41:40ZengTurkish Journal of KinesiologyTurkish Journal of Kinesiology2459-01342024-03-01101486010.31459/turkjkin.1429014649Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic reviewMuhammet Enes Yasul0https://orcid.org/0000-0002-1423-9579Vedat Çınar1https://orcid.org/0000-0003-4883-3995Yavuz Yasul2https://orcid.org/0000-0002-9458-1664Büşra Yılmaz3https://orcid.org/0000-0002-1160-2328Ömer Şenel4https://orcid.org/0000-0003-0364-9799Başakşehir Çam ve Sakura City Hospital, Nutrition and Diet UnitFIRAT UNIVERSITYONDOKUZ MAYIS UNIVERSITYGAZI UNIVERSITYGAZI UNIVERSITYThis systematic review aims to demonstrate that coenzyme Q10 (CoQ10) supplementation may be an effective molecule in improving exercise performance and recovering muscle damage, improving antioxidant capacity, and suppressing inflammatory processes. The study covers the literature in PubMed, Google Scholar, Web of Science and Scopus databases from 2011 to 2023. The final review was conducted on June 6. In the literature analysis, eight keywords (exercise, oxidative stress, CoQ10, muscle damage, inflammation, skeletal muscle, heart muscle, and performance) were employed to investigate the publications. The full texts of 362 full texts of articles were included in this study. These were analyzed according to the PRISMA reporting criteria. In the analysis, one study was conducted with experimental animals, two studies were conducted with male and female participants, and 12 studies were conducted with only male participants. Participants in twelve studies were well-trained. However, two studies were conducted with a sedentary group. In addition, CoQ10 supplementation was present in all studies. CoQ10 supplementation was between 5-60 mg/kg in 4 studies and 100 mg/kg and above in the remaining 10 studies. Antioxidant capacities and inflammation markers were among the parameters of most interest. There were fewer studies on skeletal and cardiac muscle damage and performance markers. CoQ10 supplementation during intense exercise elevates plasma CoQ10 and antioxidant levels while reducing inflammation markers. Additionally, it enhances contractile function in sarcomeres and cardiomyocytes. Nevertheless, additional studies are necessary to comprehensively as certain CoQ10 impact on athletic performance.https://dergipark.org.tr/en/download/article-file/3696472antioxidantcoenzyme q10exercise performanceinflammationheart-skeletal muscle damageoxidative stress |
| spellingShingle | Muhammet Enes Yasul Vedat Çınar Yavuz Yasul Büşra Yılmaz Ömer Şenel Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review Turkish Journal of Kinesiology antioxidant coenzyme q10 exercise performance inflammation heart-skeletal muscle damage oxidative stress |
| title | Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review |
| title_full | Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review |
| title_fullStr | Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review |
| title_full_unstemmed | Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review |
| title_short | Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review |
| title_sort | recovery response of coenzyme q10 to exercise related physiological muscle damage inflammation and oxidative stress a systematic review |
| topic | antioxidant coenzyme q10 exercise performance inflammation heart-skeletal muscle damage oxidative stress |
| url | https://dergipark.org.tr/en/download/article-file/3696472 |
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