Phospholipid derived mediators and glomerulonephritis
The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism wou...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1993-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/S0962935193000134 |
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| _version_ | 1832560733920952320 |
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| author | E. N. Wardle |
| author_facet | E. N. Wardle |
| author_sort | E. N. Wardle |
| collection | DOAJ |
| description | The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism would seem to be the more efficacious approach for the various disease entities. |
| format | Article |
| id | doaj-art-5e890d07dcdb4669934e5d3992f6439e |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1993-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-5e890d07dcdb4669934e5d3992f6439e2025-02-03T01:26:46ZengWileyMediators of Inflammation0962-93511466-18611993-01-01229910210.1155/S0962935193000134Phospholipid derived mediators and glomerulonephritisE. N. Wardle021 Common Road, North Leigh, Oxon, OX8 6RD, UKThe contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism would seem to be the more efficacious approach for the various disease entities.http://dx.doi.org/10.1155/S0962935193000134 |
| spellingShingle | E. N. Wardle Phospholipid derived mediators and glomerulonephritis Mediators of Inflammation |
| title | Phospholipid derived mediators and glomerulonephritis |
| title_full | Phospholipid derived mediators and glomerulonephritis |
| title_fullStr | Phospholipid derived mediators and glomerulonephritis |
| title_full_unstemmed | Phospholipid derived mediators and glomerulonephritis |
| title_short | Phospholipid derived mediators and glomerulonephritis |
| title_sort | phospholipid derived mediators and glomerulonephritis |
| url | http://dx.doi.org/10.1155/S0962935193000134 |
| work_keys_str_mv | AT enwardle phospholipidderivedmediatorsandglomerulonephritis |