Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease

Introduction The evolving landscape of inflammatory bowel disease (IBD) necessitates refining colonoscopic surveillance guidelines. This study outlines methodology adopted by the British Society of Gastroenterology (BSG) Guideline Development Group (GDG) for updating IBD colorectal surveillance guid...

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Main Authors: Adrian C Bateman, Bu Hayee, Sunil Dolwani, Ailsa Hart, James E East, A John Morris, Ibrahim Al Bakir, Tim Raine, Nigel J Trudgill, Anjan Dhar, Marco Novelli, Matt Rutter, Gaurav Bhaskar Nigam, Misha Kabir, Ana Wilson, Shahida Din, Venkataraman Subramanian, Neil A Shepherd, Morris Gordon, Christopher Andrew Lamb, Simon Leedham, Chris Healey, O D Faiz, Lydia White, Ruth Wakeman, Maggie Vance, Vassiliki Sinopoulou
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/11/1/e001541.full
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author Adrian C Bateman
Bu Hayee
Sunil Dolwani
Ailsa Hart
James E East
A John Morris
Ibrahim Al Bakir
Tim Raine
Nigel J Trudgill
Anjan Dhar
Marco Novelli
Matt Rutter
Gaurav Bhaskar Nigam
Misha Kabir
Ana Wilson
Shahida Din
Venkataraman Subramanian
Neil A Shepherd
Morris Gordon
Christopher Andrew Lamb
Simon Leedham
Chris Healey
O D Faiz
Lydia White
Ruth Wakeman
Maggie Vance
Vassiliki Sinopoulou
author_facet Adrian C Bateman
Bu Hayee
Sunil Dolwani
Ailsa Hart
James E East
A John Morris
Ibrahim Al Bakir
Tim Raine
Nigel J Trudgill
Anjan Dhar
Marco Novelli
Matt Rutter
Gaurav Bhaskar Nigam
Misha Kabir
Ana Wilson
Shahida Din
Venkataraman Subramanian
Neil A Shepherd
Morris Gordon
Christopher Andrew Lamb
Simon Leedham
Chris Healey
O D Faiz
Lydia White
Ruth Wakeman
Maggie Vance
Vassiliki Sinopoulou
author_sort Adrian C Bateman
collection DOAJ
description Introduction The evolving landscape of inflammatory bowel disease (IBD) necessitates refining colonoscopic surveillance guidelines. This study outlines methodology adopted by the British Society of Gastroenterology (BSG) Guideline Development Group (GDG) for updating IBD colorectal surveillance guidelines.Methods and analysis The ‘Grading of Recommendations, Assessment, Development and Evaluation’ (GRADE) approach, as outlined in the GRADE handbook, was employed. Thematic questions were formulated using either the ‘patient, intervention, comparison and outcome’ format or the ‘current state of knowledge, area of interest, potential impact and suggestions from experts in the field’ format. The evidence review process included systematic reviews assessed using appropriate appraisal tools. An extensive list of potential outcomes was compiled from literature and expert consultations and then ranked by GDG members. The top outcomes were identified for evidence synthesis in three key areas: utility of surveillance in IBD, quality of bowel preparation and use of advanced imaging techniques in colonoscopy for IBD. Risk thresholding exercises determined specific risk levels for different surveillance strategies and intervals. This approach enabled the GDG to establish precise thresholds for interventions based on relative and absolute risk assessments, directly informing the stratification of surveillance recommendations. Significance of effect sizes (small, moderate, large) will guide the final GRADE assessment of the evidence.Ethics and dissemination Ethics approval is not applicable. By integrating clinical expertise, patient experiences and innovative methodologies like risk thresholding, we aim to deliver actionable recommendations for IBD colorectal surveillance. This protocol, complementing the main guidelines, offers GDGs, clinical trialists and practitioners a framework to inform future research and enhance patient care and outcomes.
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spelling doaj-art-5e863b48e5a64f3dafc519709aba76ee2025-08-20T02:35:53ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742024-12-0111110.1136/bmjgast-2024-001541Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel diseaseAdrian C Bateman0Bu Hayee1Sunil Dolwani2Ailsa Hart3James E East4A John Morris5Ibrahim Al Bakir6Tim Raine7Nigel J Trudgill8Anjan Dhar9Marco Novelli10Matt Rutter11Gaurav Bhaskar Nigam12Misha Kabir13Ana Wilson14Shahida Din15Venkataraman Subramanian16Neil A Shepherd17Morris Gordon18Christopher Andrew Lamb19Simon Leedham20Chris Healey21O D Faiz22Lydia White23Ruth Wakeman24Maggie Vance25Vassiliki Sinopoulou26Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UKKing`s College Hospital NHS Foundation Trust, London, UKGastroenterology, Cardiff and Vale NHS Trust, Cardiff, UKSt Mark`s Hospital, London, UKNuffield Department of Medicine, University of Oxford Translational Gastroenterology Unit, Oxford, UKGastroenterology, Glasgow Royal Infirmary, Glasgow, UKGastroenterology Department, Chelsea and Westminster Hospital, London, UKCambridge University Hospitals NHS Foundation Trust, Cambridge, UKDepartment of Gastroenterology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UKGastroenterology, County Durham and Darlington NHS Foundation Trust, Darlington, UKDepartment of Histopathology, University College London, London, UKUniversity Hospital of North Tees, Stockton-on-Tees, UKUniversity of Oxford Translational Gastroenterology Unit, Oxford, UKUniversity College London, London, UKSt Mark`s Hospital and Academic Institute, London, London, UKGastroenterology, NHS Lothian, Edinburgh, UKGastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UKGloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UKBEST unit, University of Central Lancashire, Preston, UKTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UKUniversity of Oxford Translational Gastroenterology Unit, Oxford, UKGastroenterology, Airedale NHS Foundation Trust, Keighley, UKDepartment of Surgery and Cancer or Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UKNuffield Department of Medicine, University of Oxford Translational Gastroenterology Unit, Oxford, UKCrohn`s & Colitis UK, Hatfield, Hertfordshire, UKSt Mark`s Hospital and Academic Institute, London, London, UKUniversity of Central Lancashire, Preston, Lancashire, UKIntroduction The evolving landscape of inflammatory bowel disease (IBD) necessitates refining colonoscopic surveillance guidelines. This study outlines methodology adopted by the British Society of Gastroenterology (BSG) Guideline Development Group (GDG) for updating IBD colorectal surveillance guidelines.Methods and analysis The ‘Grading of Recommendations, Assessment, Development and Evaluation’ (GRADE) approach, as outlined in the GRADE handbook, was employed. Thematic questions were formulated using either the ‘patient, intervention, comparison and outcome’ format or the ‘current state of knowledge, area of interest, potential impact and suggestions from experts in the field’ format. The evidence review process included systematic reviews assessed using appropriate appraisal tools. An extensive list of potential outcomes was compiled from literature and expert consultations and then ranked by GDG members. The top outcomes were identified for evidence synthesis in three key areas: utility of surveillance in IBD, quality of bowel preparation and use of advanced imaging techniques in colonoscopy for IBD. Risk thresholding exercises determined specific risk levels for different surveillance strategies and intervals. This approach enabled the GDG to establish precise thresholds for interventions based on relative and absolute risk assessments, directly informing the stratification of surveillance recommendations. Significance of effect sizes (small, moderate, large) will guide the final GRADE assessment of the evidence.Ethics and dissemination Ethics approval is not applicable. By integrating clinical expertise, patient experiences and innovative methodologies like risk thresholding, we aim to deliver actionable recommendations for IBD colorectal surveillance. This protocol, complementing the main guidelines, offers GDGs, clinical trialists and practitioners a framework to inform future research and enhance patient care and outcomes.https://bmjopengastro.bmj.com/content/11/1/e001541.full
spellingShingle Adrian C Bateman
Bu Hayee
Sunil Dolwani
Ailsa Hart
James E East
A John Morris
Ibrahim Al Bakir
Tim Raine
Nigel J Trudgill
Anjan Dhar
Marco Novelli
Matt Rutter
Gaurav Bhaskar Nigam
Misha Kabir
Ana Wilson
Shahida Din
Venkataraman Subramanian
Neil A Shepherd
Morris Gordon
Christopher Andrew Lamb
Simon Leedham
Chris Healey
O D Faiz
Lydia White
Ruth Wakeman
Maggie Vance
Vassiliki Sinopoulou
Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
BMJ Open Gastroenterology
title Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
title_full Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
title_fullStr Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
title_full_unstemmed Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
title_short Update from 2010 (standard operating procedure): protocol for the 2024 British Society of Gastroenterology Guidelines on colorectal surveillance in inflammatory bowel disease
title_sort update from 2010 standard operating procedure protocol for the 2024 british society of gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease
url https://bmjopengastro.bmj.com/content/11/1/e001541.full
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